SCHEMBL1808575

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1808765	0.92	RBP4 (0.56)	RBP4MAPTMAPK1GRIN2DGRIN3B
	SCHEMBL1810866	0.91	RBP4 (0.59)	RBP4MAPTMAPK1GRIN2DGRIN3B
	SCHEMBL1807938	0.89	EIF4A3 (0.56)	RBP4MAPTEPHX2CNR1EIF4A3
	SCHEMBL12188570	0.86	RBP4 (0.52)	RBP4MAPTMAPK1GRIN2DGRIN3B
	SCHEMBL1808221	0.83	RBP4 (0.55)	RBP4GRIN2DGRIN3BGRIN1GRIN2A
	SCHEMBL1807211	0.81	FPR2 (0.54)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL12168202	0.79	CNR1 (0.51)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL1813014	0.78	NPC1 (0.47)	RBP4MAPTMAPK1GRIN2DGRIN3B
	SCHEMBL1809156	0.76	GRIN2D (0.50)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL1806944	0.76	HPGD (0.54)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.