SCHEMBL1808685

SCHEMBL1808685

c1ccc2cc3c(cc2c1)C3

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP3A4 P08684 3/20 0.46
TSHR P16473 3/20 0.46
HSD17B10 Q99714 3/20 0.45
TP53 P04637 2/20 0.45
MAPK1 P28482 2/20 0.45
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C9 P11712 1/20 0.45
PKM P14618 1/20 0.45
CYP2C19 P33261 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP2A6 P11509 5/20 0.44
ALOX12 P18054 1/20 0.44
NQO2 P16083 1/20 0.41
CYP1A2 P05177 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31274423 1.00 MEN1 (0.52) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL29604701 1.00 MEN1 (0.52) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL7914941 1.00 MEN1 (0.52) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL8662572 0.94 MEN1 (0.48) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL30376019 0.94 MEN1 (0.48) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL19810032 0.94 MEN1 (0.48) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL14800367 0.89 MEN1 (0.44) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL30924248 0.85 MEN1 (0.46) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL1655232 0.85 MEN1 (0.46) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL4621881 0.84 MEN1 (0.41) MEN1KMT2ACYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9388345-B2 Hydrocarbon synthesis methods, apparatus, and systems SARTEC CORPORATION (US) 2016-07-12 US disclosed
US-20140046104-A1 HYDROCARBON SYNTHESIS METHODS, APPARATUS, AND SYSTEMS SARTEC CORPORATION 2014-02-13 US disclosed
US-7951271-B2 System for recovering oil from used automobile tires THOMPSON DAVID BRENT 2011-05-31 US disclosed