SCHEMBL1655232

SCHEMBL1655232

c1ccc2cc3c(cc2c1)Cc1cc2ccccc2cc1-3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
HSD17B10 Q99714 6/20 0.45
TP53 P04637 5/20 0.45
TSHR P16473 4/20 0.45
CYP3A4 P08684 4/20 0.45
MAPK1 P28482 3/20 0.45
KDM4E B2RXH2 3/20 0.45
MAPT P10636 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C9 P11712 2/20 0.45
PKM P14618 2/20 0.45
CYP2C19 P33261 2/20 0.45
ALDH1A1 P00352 6/20 0.44
HPGD P15428 5/20 0.44
CASP1 P29466 3/20 0.44
CASP7 P55210 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30924248 1.00 MEN1 (0.46) MEN1KMT2AHSD17B10TP53TSHR
Benzo[B]Fluorene SCHEMBL599104 0.91 ALDH1A1 (0.55) MEN1KMT2AHSD17B10TP53TSHR
Benzo[B]Fluorene SCHEMBL30914260 0.91 ALDH1A1 (0.55) MEN1KMT2AHSD17B10TP53TSHR
Benzo[B]Fluorene SCHEMBL29367443 0.91 ALDH1A1 (0.55) MEN1KMT2AHSD17B10TP53TSHR
SCHEMBL23566849 0.90 MEN1 (0.43) MEN1KMT2AHSD17B10TP53TSHR
SCHEMBL12746737 0.87 MEN1 (0.41) MEN1KMT2AHSD17B10TP53TSHR
SCHEMBL4851856 0.87 SMN1; SMN2 (0.52) MEN1KMT2AHSD17B10TP53TSHR
SCHEMBL12746735 0.85 MAOA (0.54) MEN1KMT2AHSD17B10TP53TSHR
SCHEMBL10028633 0.85 TP53 (0.40) MEN1KMT2AHSD17B10TP53TSHR
SCHEMBL7914941 0.85 MEN1 (0.52) MEN1KMT2AHSD17B10TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030081432-A1 Electrolytic polymerization of aromatic hydrocarbons such as fluorene in the presence of an ester; oxidizing resulting polymer to produce a cyclopentanone-containing polymer such as poly(9-fluorenone); light emitting diodes IM&T RESEARCH, INC. 2003-05-01 US claimed
US-12637558-B2 Syndiotactic propylene-based ethylene-propylene copolymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-05-26 US disclosed
US-12378497-B2 Polypropylene viscosity modifiers and lubricating oils thereof EXXONMOBIL CHEMICALS PATENTS INC. (US) 2025-08-05 US disclosed
WO-2025042454-A1 CATALYST SYSTEM FOR ENHANCED STEREO-SPECIFICITY OF OLEFIN POLYMERIZATION FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2025-02-27 WO disclosed
WO-2025020304-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST AND USE OF CATALYST 中国石油天然气股份有限公司 2025-01-30 WO disclosed
US-20240400930-A1 Polypropylene Viscosity Modifiers and Lubricating Oils Thereof EXXONMOBILE TECH AND ENGINEERING COMPANY (US) 2024-12-05 US disclosed
US-11926802-B2 Lubricating oil composition with viscosity modifier based on syndiotactic propylene-based ethylene- propylene copolymers with improved properties EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-03-12 US disclosed
EP-4227337-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-08-16 EP disclosed
EP-4227342-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-08-16 EP disclosed
US-20230242705-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-08-03 US disclosed
US-8530712-B2 Process for producing novel synthetic basestocks EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-09-10 US disclosed
US-20130131410-A1 Process for Producing Novel Synthetic Basestocks EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-05-23 US disclosed
WO-2013072225-A1 PROCESS FOR THE PREPARATION OF HETEROPHASIC PROPYLENE POLYMER COMPOSITIONS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2013-05-23 WO disclosed
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks EXXONMOBIL CHEMICAL PATENTS INC. 2011-06-30 US disclosed
US-20110082323-A1 OLIGOMERIZATION OF OLEFIN WAXES USING METALLOCENE-BASED CATALYST SYSTEMS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-04-07 US disclosed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed
US-6239300-B1 Metallocene production process PHILLIPS PETROLEUM COMPANY 2001-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637558-B2 Syndiotactic propylene-based ethylene-propylene copolymers SDC1, SDC2, SDC4 MEN1 4561/4885KMT2A 2375/4885HSD17B10 3099/4885
US-20230242705-A1 ESTER COMPOUND AND RESIN COMPOSITION AFF4, AFF1, AFF2 MEN1 4381/4885KMT2A 322/4885HSD17B10 2319/4885
US-20130131410-A1 Process for Producing Novel Synthetic Basestocks PYM1, SCO2, SPIN4 MEN1 2463/4885KMT2A 3597/4885HSD17B10 2967/4885
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks PYM1, SPIN4, SCO2 MEN1 2848/4885KMT2A 4148/4885HSD17B10 2576/4885
US-20110082323-A1 OLIGOMERIZATION OF OLEFIN WAXES USING METALLOCENE-BASED CATALYST SYSTEMS SQLE, COG8, OSBPL8 MEN1 490/4885KMT2A 4470/4885HSD17B10 1819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.