Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MC1R | Q01726 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Dealkyl Naftifine SCHEMBL30960255 | 0.80 | MEN1 (0.54) | MC5RMAPK1MEN1KMT2AMC1R | |
| N-Dealkyl Naftifine SCHEMBL14628549 | 0.80 | MEN1 (0.54) | MC5RMAPK1MEN1KMT2AMC1R | |
| N-Dealkyl Naftifine SCHEMBL30960259 | 0.80 | MEN1 (0.54) | MC5RMAPK1MEN1KMT2AMC1R | |
| SCHEMBL20921281 | 0.79 | MC5R (0.50) | MC5RMAPK1MEN1KMT2AMC1R | |
| SCHEMBL11236863 | 0.77 | MC5R (0.41) | MC5RMAPK1MEN1KMT2AMC1R | |
| SCHEMBL7523920 | 0.77 | MC5R (0.51) | MC5RMAPK1MEN1KMT2AMC1R | |
| SCHEMBL9305839 | 0.77 | MC5R (0.58) | MC5RMAPK1MEN1KMT2AMC1R | |
| SCHEMBL11302562 | 0.75 | HPGD (0.49) | MC5RMAPK1MEN1KMT2AMC1R | |
| SCHEMBL11302558 | 0.75 | HPGD (0.49) | MC5RMAPK1MEN1KMT2AMC1R | |
| SCHEMBL18064675 | 0.74 | CYP2D6 (0.69) | MEN1KMT2ACYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160272572-A1 | ADENYLYL CYCLASE INHIBITORS FOR NEUROPATHIC AND INFLAMMATORY PAIN | PURDUE RESEARCH FOUNDATION | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272572-A1 | ADENYLYL CYCLASE INHIBITORS FOR NEUROPATHIC AND INFLAMMATORY PAIN | ADCY1, ADCY2, ADCY5 | MC5R 537/4885MAPK1 1571/4885MEN1 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.