Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18085901 | 0.85 | HDAC6 (0.46) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL18085939 | 0.80 | HDAC6 (0.68) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL18088412 | 0.78 | HDAC6 (0.67) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL21241566 | 0.76 | CXCR3 (0.38) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL18088397 | 0.74 | HDAC6 (0.61) | HDAC6HDAC3HDAC1HDAC2P2RX7 | |
| SCHEMBL18085885 | 0.68 | HDAC6 (0.57) | HDAC6HDAC3HDAC1HDAC2P2RX7 | |
| SCHEMBL10067533 | 0.68 | P2RX7 (0.67) | HDAC6HDAC3HDAC1HDAC2P2RX7 | |
| SCHEMBL20535185 | 0.65 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL23181341 | 0.65 | SMN1; SMN2 (0.49) | MEN1KMT2A | |
| SCHEMBL20535380 | 0.64 | HDAC6 (0.73) | HDAC6HDAC3HDAC1HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160271276-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | THE GENERAL HOSPITAL CORPORATION | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271276-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | HDAC1, HDAC11, HDAC3 | HDAC6 13/4885HDAC3 3/4885HDAC1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.