Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18088483 | 0.92 | TP53 (0.30) | TP53CYP1A2 | |
| SCHEMBL18088470 | 0.85 | TP53 (0.36) | TP53CYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL18909551 | 0.85 | TP53 (0.36) | TP53CYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL29850490 | 0.80 | ALDH1A1 (0.36) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL14945765 | 0.80 | ALDH1A1 (0.36) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL18088472 | 0.78 | ALDH1A1 (0.35) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL18088471 | 0.77 | TP53 (0.38) | TP53CYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL18088482 | 0.76 | KDM4E (0.30) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL20749401 | 0.76 | GAA (0.33) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL11583537 | 0.74 | ALDH1A1 (0.39) | KDM4EMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920168-B2 | Polymers of intrinsic microporosity | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-03-20 | — | — | US | disclosed |
| US-9920168-B2 | Polymers of intrinsic microporosity | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170369652-A1 | POLYMERS OF INTRINSIC MICROPOROSITY | FILMTEC CORPORATION | 2017-12-28 | — | — | US | disclosed |
| WO-2016148869-A1 | POLYMERS OF INTRINSIC MICROPOROSITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-09-22 | — | — | WO | disclosed |