SCHEMBL14945765

SCHEMBL14945765

CC1(C)CC2(CC(C)(C)c3cc(N)c(O)cc32)c2cc(O)c(N)cc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 3/20 0.36
GAA P10253 3/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
THRB P10828 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
MCL1 Q07820 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PKM P14618 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALOX15 P16050 2/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP3A4 P08684 1/20 0.34
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
FTO Q9C0B1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29850490 1.00 ALDH1A1 (0.36) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL18088472 0.98 ALDH1A1 (0.35) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL17789211 0.92 ALDH1A1 (0.32) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL11583537 0.90 ALDH1A1 (0.39) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL18088482 0.89 KDM4E (0.30) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL20749401 0.89 GAA (0.33) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL196263 0.86 RXRA (0.35) ALDH1A1KDM4EMAPTTHRBRECQL
SCHEMBL14601414 0.86 PTK2 (0.38) ALDH1A1THRBSMN1; SMN2TDP1ALOX15
SCHEMBL29569404 0.86 RXRA (0.35) ALDH1A1KDM4EMAPTTHRBRECQL
SCHEMBL18088470 0.83 TP53 (0.36) ALDH1A1KDM4EMEN1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230178848-A1 ELECTRODE SEPARATORS UNIV KING ABDULLAH SCI & TECH (SA) 2023-06-08 US disclosed
US-20230178848-A1 ELECTRODE SEPARATORS UNIV KING ABDULLAH SCI & TECH (SA) 2023-06-08 US disclosed
CN-113336773-B Spiro-bis-benzoxazole diamine, preparation method and application thereof, polyimide, preparation method and application thereof 东华大学 2022-09-13 CN disclosed
US-20220219125-A1 HYBRID INORGANIC OXIDE-CARBON MOLECULAR SIEVE MEMBRANES UNIV KING ABDULLAH SCI & TECH (SA) 2022-07-14 US disclosed
CN-113939764-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element JSR株式会社 2022-01-14 CN disclosed
CN-113336773-A Spiro-bis-benzoxazole diamine, preparation method and application thereof, polyimide, preparation method and application thereof 东华大学 2021-09-03 CN disclosed
US-10414866-B2 Troger's base polymers having intrinsic microporosity DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-17 US disclosed
EP-3016956-B1 DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE UNIV KING ABDULLAH SCI & TECH (SA) 2019-02-20 EP disclosed
US-9920168-B2 Polymers of intrinsic microporosity DOW GLOBAL TECHNOLOGIES LLC (US) 2018-03-20 US disclosed
US-20170369652-A1 POLYMERS OF INTRINSIC MICROPOROSITY FILMTEC CORPORATION 2017-12-28 US disclosed
WO-2017091357-A1 TROGER'S BASE POLYMERS HAVING INTRINSIC MICROPOROSITY DOW GLOBAL TECHNOLOGIES LLC (US) 2017-06-01 WO disclosed
US-20160367948-A1 CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES KYOTO UNIVERSITY (JP) 2016-12-22 US disclosed
US-20160367948-A1 CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES KYOTO UNIVERSITY (JP) 2016-12-22 US disclosed
US-20160152630-A1 DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2016-06-02 US disclosed
US-9273164-B2 Curing compositions for fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-01 US disclosed
US-9273164-B2 Curing compositions for fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-01 US disclosed
WO-2015001422-A2 DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2015-01-08 WO disclosed
US-20140288232-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2014-09-25 US disclosed
US-20140288232-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2014-09-25 US disclosed
WO-2013070723-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160152630-A1 DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE ALKBH3, ALK, DDC ALDH1A1 1730/4885KDM4E 391/4885MEN1 1957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.