SCHEMBL18088605

SCHEMBL18088605

CCCC1C(O)CCC1CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ CA4 P22748 1/20 0.38
▸ SLC6A12 P48065 3/20 0.36
▸ SLC6A11 P48066 3/20 0.36
▸ SLC6A13 Q9NSD5 3/20 0.36
▸ AKR1C4 P17516 1/20 0.33
▸ AKR1C3 P42330 1/20 0.33
▸ AKR1C2 P52895 1/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ HSD11B1 P28845 1/20 0.31
▸ TBXA2R P21731 1/20 0.30
▸ PTGFR P43088 1/20 0.30
▸ PTGER2 P43116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18853791 0.89 ALOX5 (0.38) CA1CA2CA4SLC6A12SLC6A11
SCHEMBL8674597 0.88 ALOX5 (0.44) ALOX5TBXA2RPTGFRPTGER2
SCHEMBL1054958 0.88 ALOX5 (0.44) ALOX5TBXA2RPTGFRPTGER2
SCHEMBL18853790 0.88 ALOX5 (0.44) ALOX5TBXA2RPTGFRPTGER2
SCHEMBL8672151 0.88 ALOX5 (0.44) ALOX5TBXA2RPTGFRPTGER2
SCHEMBL670583 0.88 ALOX5 (0.44) ALOX5TBXA2RPTGFRPTGER2
SCHEMBL8676301 0.88 ALOX5 (0.44) ALOX5TBXA2RPTGFRPTGER2
SCHEMBL8673306 0.88 ALOX5 (0.44) ALOX5TBXA2RPTGFRPTGER2
SCHEMBL8676435 0.88 ALOX5 (0.44) ALOX5TBXA2RPTGFRPTGER2
SCHEMBL22002778 0.86 ALOX5 (0.46) ALOX5TBXA2RPTGFRPTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3901129-A1 METHOD FOR SYNTHESISING NOVEL 3-HYDROXY-CYCLOPENTYL ACETIC ACID DERIVATIVE COMPOUNDS L'OREAL (FR) 2021-10-27 — — EP disclosed
US-10995051-B2 Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid L'OREAL (FR) 2021-05-04 — — US disclosed
US-10654788-B2 Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid L'OREAL (FR) 2020-05-19 — — US disclosed
US-20200131108-A1 METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYLOPENTYL ACETIC ACID L'OREAL (FR) 2020-04-30 — — US disclosed
US-20180057440-A1 METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID L'OREAL (FR) 2018-03-01 — — US disclosed
US-20180057440-A1 METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID L'OREAL (FR) 2018-03-01 — — US disclosed
WO-2016146588-A1 METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID L'OREAL (FR) 2016-09-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10654788-B2 Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid HSD17B12, FASN, AKR1C3 CA1 376/4885CA2 1267/4885CA4 802/4885
US-20180057440-A1 METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID HSD17B12, FASN, AKR1C3 CA1 376/4885CA2 1267/4885CA4 802/4885
US-10995051-B2 Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid CYP8B1, HAAO, HSD17B12 CA1 446/4885CA2 2729/4885CA4 1457/4885
US-20200131108-A1 METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYLOPENTYL ACETIC ACID CYP8B1, HAAO, HSD17B12 CA1 446/4885CA2 2729/4885CA4 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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