Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 6/20 | 1.00 |
| ▸ | ENPP1 | P22413 | 4/20 | 1.00 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 1.00 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.98 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.98 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.98 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.98 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.98 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195865 | 1.00 | P2RY1 (1.00) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL195864 | 1.00 | P2RY1 (1.00) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL10120953 | 0.99 | P2RY1 (1.00) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL29381860 | 0.99 | P2RY1 (1.00) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL375602 | 0.99 | P2RY1 (1.00) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL375601 | 0.99 | P2RY1 (1.00) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL12216627 | 0.96 | P2RY1 (0.95) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL18089712 | 0.94 | P2RY1 (0.89) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL18089797 | 0.93 | P2RY1 (1.00) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL3490789 | 0.93 | P2RY1 (0.86) | P2RY1ENPP1P2RY12P2RY11P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016147185-A1 | ADENOSINE THIOPHOSPHATE DERIVATIVES AND USES THEREOF | BAR-ILAN UNIVERSITY (IL) | 2016-09-22 | — | — | WO | disclosed |