Lactulose

Lactulose

SCHEMBL180915

OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 1.00
▸ KMT2A Q03164 2/20 1.00
▸ LGALS8 O00214 1/20 0.44
▸ LGALS3 P17931 1/20 0.44
▸ LGALS4 P56470 1/20 0.44
▸ PTPN1 P18031 2/20 0.44
▸ GJA1 P17302 1/20 0.43
▸ GJB2 P29033 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ CDK1 P06493 1/20 0.43
▸ CCNB1 P14635 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ SYNJ2 O15056 1/20 0.42
▸ TYR P14679 3/20 0.41
▸ IGF2R P11717 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactulose SCHEMBL18470690 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL18912 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL15942980 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL11892653 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL12787176 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL18479188 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL11890264 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL15942982 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL17241809 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL17623952 1.00 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116635712-A Programmable nanoreactor for random sensing (PNRSS) 南京大学 2023-08-22 — — CN claimed
US-20090082307-A1 METHOD FOR PRODUCING OLIGOPOLYSACCHARIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 2009-03-26 — — US claimed
EP-1637611-A1 Method for producing oligosaccharides CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2006-03-22 — — EP claimed
EP-1194584-B1 METHOD FOR PRODUCING OLIGOPOLYSACCHARIDES CENTRE NAT RECH SCIENT (FR) 2006-02-22 — — EP claimed
EP-1194584-A1 METHOD FOR PRODUCING OLIGOPOLYSACCHARIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2002-04-10 — — EP claimed
WO-2001004341-A1 METHOD FOR PRODUCING OLIGOPOLYSACCHARIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2001-01-18 — — WO claimed
JP-2150240-A — — None — — JP disclosed
CN-119391683-A Cellobiose epimerase mutant and application thereof 合肥工业大学 2025-02-07 — — CN disclosed
CN-116635712-A Programmable nanoreactor for random sensing (PNRSS) 南京大学 2023-08-22 — — CN disclosed
US-20210252031-A1 USE OF LACTULOSE IN THE TREATMENT OF AUTISM CUREMARK, LLC 2021-08-19 — — US disclosed
US-11033563-B2 Use of lactulose in the treatment of autism CUREMARK, LLC (US) 2021-06-15 — — US disclosed
US-20200296980-A1 METHOD OF GENERATING A SACCHARIDE CONTAINING A GALACTOSE AND A FRUCTOSE MOIETY EMPLOYING ENZYME WITH TRANSGALACTOSYLATING ACTIVITY DUPONT NUTRITION BIOSCI APS (DK) 2020-09-24 — — US disclosed
US-20200087690-A1 A METHOD OF INHIBITING ISOMERIZATION OF A REDUCING SACCHARIDE UPON THERMAL TREATMENT CHR. HANSEN A/S (DK) 2020-03-19 — — US disclosed
EP-0475160-B1 Preparation for drug application in minute droplet form IDEA AG (DE) 1996-02-14 — — EP disclosed
EP-0622374-A1 Process for the preparation of crystalline lactulose from commercial syrups INALCO S.p.A. (IT) 1994-11-02 — — EP disclosed
US-5304251-A Storage stable, solvent-free purity MORINAGA MILK INDUSTRY CO., LTD. (JP) 1994-04-19 — — US disclosed
EP-0318630-B1 Method for preparing high purity cristalline lactulose and the product obtained INALCO SPA (IT) 1993-12-29 — — EP disclosed
EP-0475160-A1 Preparation for drug application in minute droplet form Cevc, Gregor, Prof. Dr. (DE) 1992-03-18 — — EP disclosed
US-5003061-A Crystallization of lactulose from a solution of lactulose by seeding SIRAC SRL (IT) 1991-03-26 — — US disclosed
JP-H02150240-A CHEWING GUM KUDO TSUTOMU 1990-06-08 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11033563-B2 Use of lactulose in the treatment of autism SI, ALB, AADAT MEN1 2830/4885KMT2A 1854/4885LGALS8 333/4885
US-20210252031-A1 USE OF LACTULOSE IN THE TREATMENT OF AUTISM SI, ALB, AADAT MEN1 2830/4885KMT2A 1854/4885LGALS8 333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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