Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18091579 | 0.83 | HSD17B10 (0.36) | HSD17B10AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL16529385 | 0.83 | SYK (0.38) | KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL18091563 | 0.77 | MRGPRX4 (0.32) | AKR1C2AKR1C1LCKMYCNR4A1 | |
| SCHEMBL18091588 | 0.75 | LCK (0.34) | HSD17B10LCKMYCAAK1FYN | |
| SCHEMBL2377891 | 0.75 | AAK1 (0.39) | MAPTAAK1 | |
| SCHEMBL18091606 | 0.74 | HSD17B10 (0.32) | HSD17B10LCKFYN | |
| SCHEMBL16529611 | 0.73 | MMP1 (0.56) | KDM4EMMP9MMP13ALDH1A1MMP1 | |
| SCHEMBL31559586 | 0.72 | NOTUM (0.37) | HSD17B10ALDH1A1MAPTAAK1 | |
| SCHEMBL27969552 | 0.72 | KDM4E (0.44) | LCKKDM4EMYCALDH1A1MEN1 | |
| SCHEMBL27969454 | 0.71 | MYC (0.40) | HSD17B10LCKKDM4EMYCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842946-B1 | QUINAZOLINEDIONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2016-09-28 | — | — | EP | disclosed |