Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 5/20 | 0.38 |
| ▸ | CAMKK1 | Q8N5S9 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18091788 | 0.85 | PTGDR2 (0.40) | KMOPTGDR2ACMSDALDH1A1KDM4E | |
| SCHEMBL18091789 | 0.83 | PTGDR2 (0.38) | KMOPTGDR2ACMSDALDH1A1KDM4E | |
| SCHEMBL10790137 | 0.83 | ACMSD (0.50) | KMOPTGDR2ACMSDALDH1A1KDM4E | |
| SCHEMBL9403931 | 0.83 | ACMSD (0.50) | KMOPTGDR2ACMSDALDH1A1KDM4E | |
| SCHEMBL31011018 | 0.83 | ACMSD (0.50) | KMOPTGDR2ACMSDALDH1A1KDM4E | |
| SCHEMBL10790290 | 0.83 | ACMSD (0.50) | KMOPTGDR2ACMSDALDH1A1KDM4E | |
| SCHEMBL300805 | 0.83 | ACMSD (0.50) | KMOPTGDR2ACMSDALDH1A1KDM4E | |
| SCHEMBL30730923 | 0.82 | PTGDR2 (0.53) | KMOPTGDR2ACMSDALDH1A1CAMKK2 | |
| SCHEMBL50486 | 0.82 | PTGDR2 (0.53) | KMOPTGDR2ACMSDALDH1A1CAMKK2 | |
| SCHEMBL1705927 | 0.81 | KMO (0.46) | KMOPTGDR2ACMSDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699606-B1 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | BRIDGESTONE CORP (JP) | 2016-09-28 | — | — | EP | claimed |