Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18092055 | 1.00 | GABRA5 (0.31) | GABRA5CNR1 | |
| SCHEMBL18092059 | 0.90 | CNR2 (0.33) | CNR1 | |
| SCHEMBL18092013 | 0.88 | CHRM4 (0.31) | — | |
| SCHEMBL285740 | 0.85 | CNR1 (0.34) | GABRA5CNR1 | |
| SCHEMBL295219 | 0.85 | CNR1 (0.34) | GABRA5CNR1 | |
| SCHEMBL5535152 | 0.85 | CNR1 (0.34) | GABRA5CNR1 | |
| SCHEMBL18091982 | 0.85 | GABRA5 (0.35) | GABRA5 | |
| SCHEMBL18091994 | 0.84 | CHRM4 (0.34) | GABRA5 | |
| SCHEMBL18092007 | 0.83 | TP53 (0.31) | — | |
| SCHEMBL18091976 | 0.83 | ACACB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427459-B1 | ISOXAZOLE-THIAZOLE DERIVATIVES AS GABA A RECEPTOR INVERSE AGONISTS FOR USE IN THE TREATMENT OF COGNITIVE DISORDERS | HOFFMANN LA ROCHE (CH) | 2016-09-28 | — | — | EP | claimed |