Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 4/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | DDO | Q99489 | 1/20 | 0.31 |
| ▸ | BID | P55957 | 3/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.30 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.30 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838408 | 0.88 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1TSHRTDP1 | |
| SCHEMBL1834154 | 0.78 | TSHR (0.42) | GABRA1GABRB2ALDH1A1TSHRTDP1 | |
| SCHEMBL982446 | 0.75 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1TSHRTDP1 | |
| SCHEMBL1833899 | 0.74 | TSHR (0.48) | GABRA1GABRB2ALDH1A1TSHRTDP1 | |
| SCHEMBL1955828 | 0.73 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1TSHRTDP1 | |
| SCHEMBL8562009 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL1952595 | 0.72 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1TSHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL28085901 | 0.71 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1CA2 | |
| SCHEMBL707284 | 0.71 | GABRA1 (0.58) | GABRA1GABRB2ANPEPDPP4IAPP | |
| SCHEMBL30116230 | 0.71 | GABRA1 (0.58) | GABRA1GABRB2ANPEPDPP4IAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322504-B9 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2017-09-06 | — | — | EP | disclosed |
| EP-2322504-B1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2016-09-28 | — | — | EP | disclosed |