Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 11/20 | 0.97 |
| ▸ | CHRNA4 | P43681 | 10/20 | 0.97 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL1769350 | 0.91 | CHRNB2 (0.81) | CHRNB2CHRNA4CHRNA6CHRNB4CHRNA3 | |
| SCHEMBL14776660 | 0.85 | CHRNB2 (0.97) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNB1 | |
| SCHEMBL14776502 | 0.84 | CHRNB2 (0.97) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNB1 | |
| SCHEMBL7478061 | 0.77 | CHRNB4 (0.62) | CHRNB2CHRNA4CHRNA6CHRNB4CHRNA3 | |
| SCHEMBL1769198 | 0.75 | CHRNB2 (0.79) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNB1 | |
| SCHEMBL1769326 | 0.75 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNB1 | |
| SCHEMBL14776776 | 0.73 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNB1 | |
| SCHEMBL14776261 | 0.72 | CHRNB2 (0.97) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNB1 | |
| SCHEMBL1769352 | 0.70 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA6CHRNB4CHRNA3 | |
| SCHEMBL7411211 | 0.68 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA6CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513085-B1 | BICYCLIC COMPOUNDS AS ALPHA4BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2016-09-28 | — | — | EP | claimed |