SCHEMBL1809282

SCHEMBL1809282

NC(=O)c1c([O])cccc1S(N)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 15/20 0.44
CA1 P00915 13/20 0.44
CA9 Q16790 8/20 0.44
CDK2 P24941 1/20 0.44
CA6 P23280 4/20 0.41
CA5A P35218 4/20 0.41
CA4 P22748 3/20 0.41
CA12 O43570 3/20 0.41
CA7 P43166 3/20 0.41
CA5B Q9Y2D0 3/20 0.41
CA14 Q9ULX7 2/20 0.41
CYP2C9 P11712 1/20 0.41
STAT3 P40763 1/20 0.40
MAPK1 P28482 1/20 0.37
CA3 P07451 1/20 0.37
CA13 Q8N1Q1 1/20 0.37
LDHA P00338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1804840 0.85 CDK2 (0.44) CA2CA1CA9CDK2CA6
SCHEMBL1806010 0.85 TTR (0.43) CA2CA1CA9CDK2
SCHEMBL1809283 0.82 CDK2 (0.55) CA2CA1CA9CDK2CA6
SCHEMBL23849489 0.81 CA2 (0.49) CA2CA1CA9CDK2CA6
SCHEMBL9657062 0.78 F2 (0.47) CA2CA1CA9CDK2CA6
SCHEMBL7332948 0.75 CA1 (0.50) CA2CA1CA9CDK2CA6
SCHEMBL17597050 0.73 PTGES2 (0.40) CA2CA1CA9CA6CA5A
SCHEMBL1808913 0.72 CA2 (0.58) CA2CA1CA9CDK2CA6
SCHEMBL11203939 0.71 STAT3 (0.39) CA2CA1CA9CDK2STAT3
SCHEMBL17597051 0.71 CA2 (0.45) CA2CA1CA9CA6CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 CA2 1279/4885CA1 798/4885CA9 1071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.