SCHEMBL1809362

SCHEMBL1809362

Nc1ccc(S(=O)(=O)O)c2ccc(S(=O)(=O)O)cc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
HSD17B10 Q99714 4/20 0.57
CASP6 P55212 3/20 0.57
CYP2C9 P11712 2/20 0.57
CYP2C19 P33261 2/20 0.57
TTR P02766 1/20 0.53
SENP2 Q9HC62 5/20 0.50
SENP3 Q9H4L4 4/20 0.50
SENP1 Q9P0U3 4/20 0.50
SUMO2 P61956 3/20 0.50
SUMO1 P63165 3/20 0.50
SENP7 Q9BQF6 3/20 0.50
PHLPP2 Q6ZVD8 1/20 0.49
AURKA O14965 1/20 0.46
AURKB Q96GD4 1/20 0.46
NT5E P21589 3/20 0.44
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 3/20 0.43
NSD2 O96028 2/20 0.42
DUSP3 P51452 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621937 1.00 ALDH1A1 (0.57) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL9314959 0.97 TTR (0.54) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL1807549 0.93 ALDH1A1 (0.57) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL30460486 0.93 ALDH1A1 (0.57) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL20497215 0.91 ALDH1A1 (0.56) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL6051371 0.89 ALDH1A1 (0.59) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL6240856 0.87 AURKA (0.57) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL3296584 0.87 ALDH1A1 (0.52) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL30939652 0.87 ALDH1A1 (0.52) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL20735785 0.86 SENP2 (0.63) ALDH1A1HSD17B10CYP2C9CYP2C19TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024218102-A1 MODIFICATION OF AROMATIC POLYMERS PREFERE RESINS HOLDING GMBH (DE) 2024-10-24 WO claimed
EP-4450530-A1 MODIFIED RESINS BASED ON RESINOUS OLIGOMERIC OR POLYMERIC PHENOLIC MATERIALS Prefere Resins Holding GmbH (DE) 2024-10-23 EP claimed
CN-103687848-B Sustainable chemical process for separation of naphthalene sulfonic acid compounds using intrinsic recycle of all acidic streams generated during separation and washing 布哈德莱什·K·帕迪亚 2018-04-24 CN claimed
WO-2012147037-A2 SUSTAINABLE CHEMICAL PROCESS FOR ISOLATION OF NAPHTHALENE SULPHONIC ACID COMPOUNDS WITH INHERENT RECYCLE OF ALL ACIDIC STREAMS GENERATED DURING ISOLATION AND WASHING PADIA BHADRESH K (IN) 2012-11-01 WO claimed
EP-0048692-B1 AZO COUPLING PROCESS CIBA-GEIGY AG (CH) 1984-04-18 EP claimed
EP-0037509-B1 PROCESS FOR THE PREPARATION OF 1-NAPHTHYLAMINE-4,7-DISULFONIC ACID BAYER AG (DE) 1983-04-13 EP claimed
EP-0037511-B1 PROCESS FOR THE ISOLATION OF 1-NAPHTHYLAMINE-4,6 AND 1-NAPHTHYLAMINE-4,7-DISULFONIC ACIDS BAYER AG (DE) 1983-02-16 EP claimed
US-4348336-A Process for the isolation of 1-naphthylamine-4,6- and 1-naphthylamine-4,7-disulphonic acid BAYER AKTIENGESELLSCHAFT (DE) 1982-09-07 US claimed
EP-0048692-A1 Azo coupling process CIBA-GEIGY AG (CH) 1982-03-31 EP claimed
EP-0037511-A1 Process for the isolation of 1-naphthylamine-4,6 and 1-naphthylamine-4,7-disulfonic acids BAYER AG (DE) 1981-10-14 EP claimed
EP-0037509-A1 Process for the preparation of 1-naphthylamine-4,7-disulfonic acid BAYER AG (DE) 1981-10-14 EP claimed
US-4091013-A Process for preparing 1-amino-naphthalene-7-sulphonic acid BAYER AKTIENGESELLSCHAFT (DT) 1978-05-23 US claimed
EP-4574815-A1 PROCESS FOR THE SEPARATION OF AROMATIC SULPHONIC ACIDS AND SALTS FROM AQUEOUS PHASES Saltigo GmbH (DE) 2025-06-25 EP disclosed
US-12331096-B2 Binding domain mapping and compounds, compositions, complexes, methods, and kits related thereto George Mason Research Foundation, Inc. (US) 2025-06-17 US disclosed
WO-2024218102-A1 MODIFICATION OF AROMATIC POLYMERS PREFERE RESINS HOLDING GMBH (DE) 2024-10-24 WO disclosed
EP-4450530-A1 MODIFIED RESINS BASED ON RESINOUS OLIGOMERIC OR POLYMERIC PHENOLIC MATERIALS Prefere Resins Holding GmbH (DE) 2024-10-23 EP disclosed
US-4163675-A CONTAINING NAPHTHALENE DERIVATIVES PILOT INK CO., LTD. (JP) 1979-08-07 US disclosed
US-4129590-A INHIBITORS OF THE COMPLEMENT SYSTEM AMERICAN CYANAMID COMPANY (US) 1978-12-12 US disclosed
US-4091013-A Process for preparing 1-amino-naphthalene-7-sulphonic acid BAYER AKTIENGESELLSCHAFT (DT) 1978-05-23 US disclosed
US-4061627-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1977-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331096-B2 Binding domain mapping and compounds, compositions, complexes, methods, and kits related thereto SNRPE, SSBP1, RPA1 ALDH1A1 4743/4885HSD17B10 3628/4885CASP6 3035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.