Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 16/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 18/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18059756 | 0.92 | NQO2 (0.47) | NQO1MITFNQO2 | |
| SCHEMBL18095058 | 0.78 | NQO2 (0.48) | NQO1MITFNQO2NSD2SMARCA2 | |
| Temacrazine SCHEMBL14259457 | 0.70 | NQO2 (0.76) | NQO1MITFNQO2 | |
| SCHEMBL18095068 | 0.70 | NQO2 (0.47) | NQO1NQO2NSD2SMARCA2 | |
| SCHEMBL13498768 | 0.64 | NQO1 (0.72) | NQO1MITFNQO2NSD2SMARCA2 | |
| SCHEMBL14259712 | 0.63 | NQO2 (0.66) | NQO1MITFNQO2 | |
| Hydrochloric Acid SCHEMBL18059766 | 0.63 | NQO1 (0.74) | NQO1MITFNQO2NSD2SMARCA2 | |
| SCHEMBL14259715 | 0.62 | NQO2 (0.62) | NQO1MITFNQO2 | |
| SCHEMBL14291793 | 0.61 | NQO2 (0.69) | NQO1MITFNQO2NSD2SMARCA2 | |
| SCHEMBL14301525 | 0.61 | NQO2 (0.68) | NQO1MITFNQO2NSD2SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016150799-A1 | ASYMMETRIC BIS-ACRIDINES WITH ANTITUMOUR ACTIVITY AND THEIR USES | Politechnika Gdańska (PL) | 2016-09-29 | — | — | WO | disclosed |