Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 18/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 3/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095058 | 0.93 | NQO2 (0.48) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL7220854 | 0.78 | NQO2 (0.71) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| Hydrochloric Acid SCHEMBL18059756 | 0.76 | NQO2 (0.47) | NQO2NQO1 | |
| SCHEMBL13916795 | 0.75 | NQO2 (0.68) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL753153 | 0.74 | NQO2 (0.66) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL13916807 | 0.73 | NQO2 (0.64) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL753152 | 0.71 | NQO2 (0.61) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL18095047 | 0.70 | NQO1 (0.45) | NQO2SMARCA2NSD2NQO1 | |
| SCHEMBL7064396 | 0.69 | NQO2 (0.49) | NQO2SMARCA2NSD2 | |
| SCHEMBL29406123 | 0.69 | NQO2 (0.49) | NQO2SMARCA2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016150799-A1 | ASYMMETRIC BIS-ACRIDINES WITH ANTITUMOUR ACTIVITY AND THEIR USES | Politechnika Gdańska (PL) | 2016-09-29 | — | — | WO | claimed |