Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 16/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095068 | 0.93 | NQO2 (0.47) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL18095047 | 0.78 | NQO1 (0.45) | NQO2SMARCA2NSD2NQO1MITF | |
| SCHEMBL14291793 | 0.74 | NQO2 (0.69) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL5132229 | 0.73 | NQO2 (0.67) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL13526710 | 0.72 | NQO2 (0.70) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL7064402 | 0.71 | NQO2 (0.51) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL13526702 | 0.70 | NQO2 (0.70) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL7220854 | 0.70 | NQO2 (0.71) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| Hydrochloric Acid SCHEMBL18059756 | 0.70 | NQO2 (0.47) | NQO2NQO1MITF | |
| SCHEMBL13526651 | 0.70 | NQO2 (0.69) | NQO2SMARCA2NSD2NQO1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016150799-A1 | ASYMMETRIC BIS-ACRIDINES WITH ANTITUMOUR ACTIVITY AND THEIR USES | Politechnika Gdańska (PL) | 2016-09-29 | — | — | WO | disclosed |