SCHEMBL18095578

SCHEMBL18095578

Nc1nc2c(ncn2[C@H]2CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.60
▸ P2RY2 P41231 1/20 0.56
▸ P2RY4 P51582 1/20 0.56
▸ P2RY6 Q15077 1/20 0.56
▸ POLG P54098 2/20 0.55
▸ TGM2 P21980 1/20 0.55
▸ PNP P00491 3/20 0.54
▸ FUT5 Q11128 1/20 0.53
▸ KRAS P01116 2/20 0.52
▸ NT5E P21589 1/20 0.50
▸ POLA1 P09884 1/20 0.48
▸ HPRT1 P00492 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ ALB P02768 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ P2RX3 P56373 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dideoxy Guanosine Triphosphate SCHEMBL80109 1.00 POLB (0.60) POLBP2RY2P2RY4P2RY6POLG
Dideoxy Guanosine Triphosphate SCHEMBL24370775 1.00 POLB (0.60) POLBP2RY2P2RY4P2RY6POLG
Dideoxy Guanosine Triphosphate SCHEMBL25720613 1.00 POLB (0.60) POLBP2RY2P2RY4P2RY6POLG
Dideoxy Guanosine Triphosphate SCHEMBL25712486 1.00 POLB (0.60) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL4968018 0.99 POLB (0.61) POLBP2RY2P2RY4P2RY6POLG
Dideoxy Guanosine Triphosphate SCHEMBL6915085 0.94 POLB (0.54) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL26855308 0.93 POLB (0.54) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL27378463 0.93 POLB (0.54) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL19662102 0.93 POLB (0.66) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL1762945 0.92 POLB (0.57) POLBP2RY2P2RY4P2RY6POLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922968-B Polymer-labeled nucleotides for single-molecule electronic SNP assays 哥伦比亚大学董事会 2022-05-17 — — CN disclosed
EP-3274471-A1 POLYMER TAGGED NUCLEOTIDES FOR SINGLE MOLECULE ELECTRONIC SNP ASSAY The Trustees of Columbia University in the City of New York (US) 2018-01-31 — — EP disclosed
WO-2016154215-A1 POLYMER TAGGED NUCLEOTIDES FOR SINGLE MOLECULE ELECTRONIC SNP ASSAY THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-09-29 — — WO disclosed
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