Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.56 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.56 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.56 |
| ▸ | POLG | P54098 | 2/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | PNP | P00491 | 3/20 | 0.54 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 2/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dideoxy Guanosine Triphosphate SCHEMBL80109 | 1.00 | POLB (0.60) | POLBP2RY2P2RY4P2RY6POLG | |
| Dideoxy Guanosine Triphosphate SCHEMBL25720613 | 1.00 | POLB (0.60) | POLBP2RY2P2RY4P2RY6POLG | |
| Dideoxy Guanosine Triphosphate SCHEMBL25712486 | 1.00 | POLB (0.60) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL18095578 | 1.00 | POLB (0.60) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL4968018 | 0.99 | POLB (0.61) | POLBP2RY2P2RY4P2RY6POLG | |
| Dideoxy Guanosine Triphosphate SCHEMBL6915085 | 0.94 | POLB (0.54) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL26855308 | 0.93 | POLB (0.54) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL27378463 | 0.93 | POLB (0.54) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL19662102 | 0.93 | POLB (0.66) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL1762945 | 0.92 | POLB (0.57) | POLBP2RY2P2RY4P2RY6POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |
| WO-2022083686-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | 深圳华大生命科学研究院 | 2022-04-28 | — | — | WO | disclosed |