⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033448 | 1.00 | — | — | |
| SCHEMBL58409 | 1.00 | — | — | |
| SCHEMBL11585608 | 0.97 | — | — | |
| SCHEMBL3165379 | 0.82 | PTGS1 (0.43) | — | |
| Cystine SCHEMBL15667872 | 0.80 | PTGS1 (0.58) | — | |
| SCHEMBL8430872 | 0.77 | — | — | |
| SCHEMBL23897439 | 0.75 | — | — | |
| Cysteine SCHEMBL5705426 | 0.75 | PTGS1 (1.00) | — | |
| SCHEMBL358881 | 0.75 | — | — | |
| SCHEMBL692227 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473483-B | Compounds for medical use | 奥斯维尔医疗私人有限公司 | 2022-08-30 | — | — | CN | disclosed |
| US-10858389-B2 | Solution phase method for preparing etelcalcetide | AMGEN INC. (US) | 2020-12-08 | — | — | US | disclosed |
| EP-3274360-B1 | SOLUTION PHASE METHOD FOR PREPARING ETELCALCETIDE | AMGEN INC (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20180079777-A1 | SOLUTION PHASE METHOD FOR PREPARING ETELCALCETIDE | AMGEN INC. | 2018-03-22 | — | — | US | disclosed |
| EP-3274360-A1 | SOLUTION PHASE METHOD FOR PREPARING ETELCALCETIDE | Amgen Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016154580-A1 | SOLUTION PHASE METHOD FOR PREPARING ETELCALCETIDE | AMGEN INC. (US) | 2016-09-29 | — | — | WO | disclosed |