⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692228 | 1.00 | — | — | |
| Cysteine SCHEMBL27977650 | 0.79 | PTGS1 (0.94) | — | |
| SCHEMBL16690306 | 0.79 | — | — | |
| Cysteine SCHEMBL30525215 | 0.79 | — | — | |
| SCHEMBL12015634 | 0.77 | — | — | |
| Cysteine SCHEMBL28172077 | 0.77 | — | — | |
| SCHEMBL13594047 | 0.77 | — | — | |
| SCHEMBL358881 | 0.75 | — | — | |
| SCHEMBL5555288 | 0.75 | — | — | |
| Cysteine SCHEMBL4289403 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659687-A | Delayed release compositions of linaclotide | 硬木药品公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104053449-A | Treatments for gastrointestinal disorders | IRONWOOD PHARMACEUTICALS INC | 2014-09-17 | — | — | CN | claimed |
| JP-2004501784-A | — | — | 2004-01-22 | — | — | JP | claimed |
| EP-1297010-A2 | BIOELASTOMER NANOMACHINES AND BIOSENSORS | BIOELASTICS RESEARCH, LTD. (US) | 2003-04-02 | — | — | EP | claimed |
| US-20020068304-A1 | Bioelastomer nanomachines and biosensors | BIOELASTICS RESEARCH, LTD. | 2002-06-06 | — | — | US | claimed |
| WO-2002000686-A2 | BIOELASTOMER NANOMACHINES AND BIOSENSORS | BIOELASTICS RESEARCH, LTD. (US) | 2002-01-03 | — | — | WO | claimed |
| US-6335176-B1 | REAGENT IS SUCCINIMIDYL MOIETY LINKED TO KINASE SUBSTRATE; CAN BE LINKED TO FREE PRIMARY OR SECONDARY AMINE IN COMPOUND TO BE PHOSPHORYLATED | PHARMACOPEIA, INC. | 2002-01-01 | — | — | US | claimed |
| US-5132402-A | Immobilized peptide which binds to human antibody to nicotinic acetylcholine receptor | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1992-07-21 | — | — | US | claimed |
| US-4889917-A | TREATMENT OF MYASTHENIA GRAVIS | AGENCY OF INDUSTRIAL SCIENCE TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) | 1989-12-26 | — | — | US | claimed |
| EP-0318240-A2 | Peptide, adsorbent, method for production thereof, and method for use thereof | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) | 1989-05-31 | — | — | EP | claimed |
| WO-2025101983-A1 | NON-STEROIDAL ISONITRILE BINDING COMPOUNDS OF CYTOCHROME P450 SUBTYPES | BRANDEIS UNIVERSITY (US) | 2025-05-15 | — | — | WO | disclosed |
| US-20240368212-A1 | SELECTIVE ISONITRILE INHIBITORS OF CYTOCHROME P450 SUBTYPES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-11-07 | — | — | US | disclosed |
| EP-4392036-A1 | SELECTIVE ISONITRILE INHIBITORS OF CYTOCHROME P450 SUBTYPES | Brandeis University (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028205-A1 | SELECTIVE ISONITRILE INHIBITORS OF CYTOCHROME P450 SUBTYPES | BRANDEIS UNIVERSITY (US) | 2023-03-02 | — | — | WO | disclosed |
| US-20220263033-A1 | ETCHING PROCESS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2022-08-18 | — | — | US | disclosed |
| US-4351764-A | Process for the selective formation of disulfide bridges in polypeptides and therapeutic compositions | der Wissenschaften e.V. Max-Planck-Gesellschaft zur/Forderung (DE) | 1982-09-28 | — | — | US | disclosed |
| US-4328135-A | Octapeptides lowering growth hormone | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |
| US-4282143-A | Octapeptides lowering growth hormone | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4225472-A | Truncated somatostatin analogs | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-09-30 | — | — | US | disclosed |
| US-4185010-A | SOMATOSTATIN ANALOGUES; ANTIDIABETIC AND HYPOGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-01-22 | — | — | US | disclosed |