Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18098168 | 0.83 | CA9 (0.47) | CA9CA2CA12CA1CA7 | |
| SCHEMBL4376931 | 0.81 | CA9 (0.57) | CA9CA2CA12CA1CA7 | |
| SCHEMBL18068758 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTGAAKDM4EMAPK1 | |
| SCHEMBL3676125 | 0.71 | CA9 (0.69) | CA9CA2CA12CA1CA7 | |
| SCHEMBL16633168 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAKDM4EMAPK1 | |
| SCHEMBL12172936 | 0.66 | CA9 (0.60) | CA9CA2CA12CA1CA7 | |
| SCHEMBL19213224 | 0.66 | ALDH1A1 (0.44) | ALDH1A1MAPTGAAKDM4EMAPK1 | |
| SCHEMBL3946527 | 0.65 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EMAPK1MEN1 | |
| SCHEMBL13018335 | 0.65 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EMAPK1MEN1 | |
| SCHEMBL13018337 | 0.65 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035882-B2 | Flame retardant PHT compositions | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-07-31 | — | — | US | disclosed |
| US-20160362520-A1 | FLAME RETARDANT PHT COMPOSITIONS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-12-15 | — | — | US | disclosed |
| US-9453108-B2 | Flame retardant PHT compositions | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-09-27 | — | — | US | disclosed |