Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18098108 | 0.86 | CYP2C19 (0.49) | LMNAHSD17B10CRHBPCRHR2MEN1 | |
| SCHEMBL3036448 | 0.84 | EPHX1 (0.59) | EPHX1LMNAHSD17B10TRPM8ALOX5 | |
| Fenbutyramide SCHEMBL1477997 | 0.83 | EPHX1 (0.63) | EPHX1LMNAHSD17B10CRHBPCRHR2 | |
| Fenbutyramide SCHEMBL1478462 | 0.83 | EPHX1 (0.63) | EPHX1LMNAHSD17B10CRHBPCRHR2 | |
| Fenbutyramide SCHEMBL232920 | 0.83 | EPHX1 (0.63) | EPHX1LMNAHSD17B10CRHBPCRHR2 | |
| Fenbutyramide SCHEMBL15995561 | 0.82 | EPHX1 (0.61) | EPHX1LMNAHSD17B10CRHBPCRHR2 | |
| SCHEMBL2183709 | 0.77 | EPHX1 (0.59) | EPHX1LMNAHSD17B10TRPM8ALOX5 | |
| SCHEMBL22322995 | 0.77 | EPHX1 (0.59) | EPHX1LMNABCAT2SMN1; SMN2 | |
| SCHEMBL28295013 | 0.76 | ALDH1A1 (0.52) | EPHX1LMNAHSD17B10ALDH1A1POLB | |
| SCHEMBL6158397 | 0.75 | GRM2 (0.59) | EPHX1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170170008-A1 | PATTERN TREATMENT METHODS | DOW GLOBAL TECHNOLOGIES LLC | 2017-06-15 | — | — | US | disclosed |
| US-9455177-B1 | Contact hole formation methods | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-09-27 | — | — | US | disclosed |