Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.59 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | KYNU | Q16719 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5286288 | 0.89 | GRM2 (0.62) | GRM2GRM3EPHX1SLC1A1SLC1A2 | |
| SCHEMBL6448129 | 0.89 | GRM2 (0.62) | GRM2GRM3EPHX1SLC1A1SLC1A2 | |
| SCHEMBL8558695 | 0.84 | GRM2 (0.57) | GRM2GRM3EPHX1SLC1A1SLC1A2 | |
| SCHEMBL7494984 | 0.82 | KMT2A (0.50) | GRM2GRM3EPHX1PKMBCAT2 | |
| Hydrochloric Acid SCHEMBL7494979 | 0.80 | EPHX1 (0.49) | GRM2GRM3EPHX1PKMBCAT2 | |
| SCHEMBL5282418 | 0.80 | GRM2 (0.79) | GRM2GRM3SLC1A1SLC1A2SLC1A3 | |
| SCHEMBL3036448 | 0.79 | EPHX1 (0.59) | EPHX1PKMCYP2C19BCAT2 | |
| SCHEMBL22322995 | 0.79 | EPHX1 (0.59) | GRM2GRM3EPHX1PKMCYP2C19 | |
| SCHEMBL28640680 | 0.79 | CYP2C19 (0.53) | GRM2GRM3EPHX1ALPIPKM | |
| SCHEMBL9065063 | 0.77 | KYNU (0.70) | GRM2GRM3SLC1A1SLC1A2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856513-B1 | Thalidomide analogues from the piperidine-2,6-dione class | GRUENENTHAL GMBH (DE) | 2005-11-30 | — | — | EP | disclosed |
| EP-0856513-A2 | Thalidomide analogues from the piperidine-2,6-dione class | Grünenthal GmbH (DE) | 1998-08-05 | — | — | EP | disclosed |