SCHEMBL18098161

COC[C@@H](C)O[C@H]1C(O)[C@@H](CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)O[C@H]1N(/C=C(/C)C(C)=O)C(C)=O

nearest known ligand 0.35

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	SMYD2	Q9NRG4	2/20	0.33

▸	CYP3A4	P08684	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15170660	1.00	SMYD2 (0.33)	SMYD2CYP3A4
SCHEMBL16947992	0.90	SMYD2 (0.31)	SMYD2
SCHEMBL16947991	0.90	SMYD2 (0.31)	SMYD2
SCHEMBL15170284	0.90	SMYD2 (0.31)	SMYD2
SCHEMBL16947988	0.90	SMYD2 (0.31)	SMYD2
SCHEMBL15170709	0.89	SMYD2 (0.31)	SMYD2
SCHEMBL15170671	0.79	MAPK1 (0.37)	—
SCHEMBL14828604	0.75	—	—
SCHEMBL14902887	0.73	—	—
SCHEMBL14929751	0.73	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9453043-B2	Nucleic acid chemical modifications	ALNYLAM PHARMACEUTICALS, INC. (US)	2016-09-27	—	—	US	disclosed