Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 4/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 4/20 | 0.32 |
| ▸ | HTR6 | P50406 | 4/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18099438 | 0.92 | RARA (0.31) | HTR1ADRD2HTR7HTR6 | |
| SCHEMBL18099448 | 0.90 | HTR1A (0.33) | CHEK1PDPK1JAK2MAPK8EGFR | |
| SCHEMBL9250941 | 0.90 | HTR1A (0.31) | CHEK1PDPK1JAK2MAPK8EGFR | |
| SCHEMBL18099433 | 0.90 | KCNH2 (0.31) | CHEK1PDPK1JAK2MAPK8EGFR | |
| SCHEMBL9289952 | 0.88 | HTR1A (0.30) | HTR1ADRD2HTR7HTR6 | |
| SCHEMBL18099437 | 0.87 | — | — | |
| SCHEMBL8510919 | 0.87 | FFAR4 (0.32) | — | |
| SCHEMBL18091463 | 0.87 | AKT1 (0.33) | CHEK1CDK2 | |
| SCHEMBL18102226 | 0.85 | PIK3CA (0.31) | CHEK1 | |
| SCHEMBL18099435 | 0.84 | USP2 (0.32) | HTR1ACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160279886-A1 | METHOD OF FORMING A PHOTOCHROMIC SEGMENTED MULTIFOCAL LENS | TRANSITIONS OPTICAL, INC. | 2016-09-29 | — | — | US | disclosed |