Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.40 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932937 | 0.87 | XDH (0.64) | XDHKDM4EALDH1A1HSD17B10HPGDS | |
| SCHEMBL18100450 | 0.81 | ATM (0.61) | XDHKDM4EALDH1A1HSD17B10HPGDS | |
| SCHEMBL18103155 | 0.80 | RAF1 (0.47) | KDM4EALDH1A1HPGDSFOLH1 | |
| SCHEMBL13702135 | 0.79 | KDM4E (0.62) | XDHKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL31226783 | 0.79 | XDH (0.56) | XDHKDM4EALDH1A1HSD17B10HPGDS | |
| SCHEMBL25820302 | 0.79 | XDH (0.56) | XDHKDM4EALDH1A1HSD17B10HPGDS | |
| SCHEMBL2247463 | 0.77 | ATM (0.65) | XDHKDM4EALDH1A1LMNAGAA | |
| SCHEMBL24883479 | 0.76 | CASP3 (0.53) | XDHKDM4EALDH1A1HSD17B10FOLH1 | |
| SCHEMBL12314959 | 0.76 | XDH (0.47) | XDHKDM4EALDH1A1HSD17B10HPGDS | |
| SCHEMBL16725467 | 0.76 | FOLH1 (0.49) | KDM4EALDH1A1HSD17B10HPGDSFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793895-B2 | Residualizing linkers and uses thereof | CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION | 2023-10-24 | — | — | US | disclosed |
| US-11793895-B2 | Residualizing linkers and uses thereof | CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION | 2023-10-24 | — | — | US | disclosed |
| US-20210060190-A1 | RESIDUALIZING LINKERS AND USES THEREOF | CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION (CA) | 2021-03-04 | — | — | US | disclosed |
| US-10758636-B2 | Residualizing linkers and uses thereof | CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION (CA) | 2020-09-01 | — | — | US | disclosed |
| US-20160279272-A1 | RESIDUALIZING LINKERS AND USES THEREOF | CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION (CA) | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210060190-A1 | RESIDUALIZING LINKERS AND USES THEREOF | CD44, CD47, MTCL3 | XDH 2379/4885KDM4E 937/4885ALDH1A1 619/4885 |
| US-20160279272-A1 | RESIDUALIZING LINKERS AND USES THEREOF | CD44, CD47, MTCL3 | XDH 2379/4885KDM4E 937/4885ALDH1A1 619/4885 |
| US-10758636-B2 | Residualizing linkers and uses thereof | CD44, CD47, MTCL3 | XDH 2379/4885KDM4E 937/4885ALDH1A1 619/4885 |
| US-11793895-B2 | Residualizing linkers and uses thereof | CD44, CD47, MTCL3 | XDH 2379/4885KDM4E 937/4885ALDH1A1 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.