Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 13/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810101 | 1.00 | AKT1 (0.46) | AKT1BRD4HSD17B10MEN1GAA | |
| SCHEMBL1810103 | 1.00 | AKT1 (0.46) | AKT1BRD4HSD17B10MEN1GAA | |
| SCHEMBL1810709 | 0.90 | AKT1 (0.48) | AKT1BRD4MEN1GAAKMT2A | |
| SCHEMBL1810704 | 0.90 | AKT1 (0.48) | AKT1BRD4MEN1GAAKMT2A | |
| SCHEMBL1810707 | 0.90 | AKT1 (0.48) | AKT1BRD4MEN1GAAKMT2A | |
| SCHEMBL315177 | 0.88 | AKT1 (0.37) | AKT1HSD17B10 | |
| SCHEMBL315176 | 0.88 | AKT1 (0.37) | AKT1HSD17B10 | |
| SCHEMBL315178 | 0.88 | AKT1 (0.37) | AKT1HSD17B10 | |
| SCHEMBL313665 | 0.86 | OXTR (0.43) | AKT1BRD4HSD17B10MEN1GAA | |
| SCHEMBL313664 | 0.86 | OXTR (0.43) | AKT1BRD4HSD17B10MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322527-A1 | Triazole derivatives | Merck Patent GmbH (DE) | 2011-05-18 | — | — | EP | disclosed |