Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810707 | 1.00 | AKT1 (0.48) | AKT1BRD4TNKS2MEN1GAA | |
| SCHEMBL1810704 | 1.00 | AKT1 (0.48) | AKT1BRD4TNKS2MEN1GAA | |
| SCHEMBL1810105 | 0.90 | AKT1 (0.46) | AKT1BRD4MEN1GAAKMT2A | |
| SCHEMBL1810103 | 0.90 | AKT1 (0.46) | AKT1BRD4MEN1GAAKMT2A | |
| SCHEMBL1810101 | 0.90 | AKT1 (0.46) | AKT1BRD4MEN1GAAKMT2A | |
| SCHEMBL313665 | 0.88 | OXTR (0.43) | AKT1BRD4MEN1GAAKMT2A | |
| SCHEMBL313663 | 0.88 | OXTR (0.43) | AKT1BRD4MEN1GAAKMT2A | |
| SCHEMBL313664 | 0.88 | OXTR (0.43) | AKT1BRD4MEN1GAAKMT2A | |
| SCHEMBL316637 | 0.87 | AKT1 (0.36) | AKT1TNKS2GAAAVPR1A | |
| SCHEMBL316638 | 0.87 | AKT1 (0.36) | AKT1TNKS2GAAAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322527-A1 | Triazole derivatives | Merck Patent GmbH (DE) | 2011-05-18 | — | — | EP | claimed |
| EP-2322527-A1 | Triazole derivatives | Merck Patent GmbH (DE) | 2011-05-18 | — | — | EP | disclosed |