SCHEMBL18101131

SCHEMBL18101131

Brc1cc2c3ccccc3n(-c3ccccc3)c2c2sc3ccccc3c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ PTPN1 P18031 3/20 0.37
▸ HSD17B10 Q99714 2/20 0.37
▸ PTPRC P08575 1/20 0.35
▸ PTPRF P10586 1/20 0.35
▸ PTPRA P18433 1/20 0.35
▸ PTPRB P23467 1/20 0.35
▸ PTPN6 P29350 1/20 0.35
▸ DUSP3 P51452 1/20 0.35
▸ PTPN12 Q05209 1/20 0.35
▸ MEN1 O00255 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ GAA P10253 1/20 0.34
▸ RXFP1 Q9HBX9 4/20 0.34
▸ MAPT P10636 3/20 0.34
▸ TP53 P04637 5/20 0.32
▸ POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18101424 0.93 PTPN1 (0.37) ATMKDM4EL3MBTL1PTPN1HSD17B10
SCHEMBL20175709 0.91 PTPN1 (0.36) ATMKDM4EL3MBTL1PTPN1HSD17B10
SCHEMBL18101099 0.90 ATM (0.44) ATMKDM4EL3MBTL1PTPN1HSD17B10
SCHEMBL20175696 0.87 PMM2 (0.37) PTPN1PTPRCPTPRFPTPRAPTPRB
SCHEMBL20175700 0.84 ATM (0.40) ATMKDM4EL3MBTL1PTPN1HSD17B10
SCHEMBL20175695 0.84 PTPN1 (0.35) PTPN1PTPRCPTPRFPTPRAPTPRB
SCHEMBL18101427 0.83 ATM (0.38) ATMKDM4EL3MBTL1PTPN1HSD17B10
SCHEMBL19889629 0.83 ESR2 (0.34) KDM4EPTPN1MEN1ALDH1A1KMT2A
SCHEMBL29573220 0.83 ATM (0.45) ATMKDM4EL3MBTL1PTPN1HSD17B10
SCHEMBL18101367 0.83 PTPN1 (0.37) ATMKDM4EL3MBTL1PTPN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266787-B1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO LTD (KR) 2022-07-06 — — EP disclosed
US-10717744-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2020-07-21 — — US disclosed
WO-2020085793-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2020-04-30 — — WO disclosed
US-20180201621-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-07-19 — — US disclosed
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed
WO-2018034444-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2018-02-22 — — WO disclosed
WO-2016153198-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF 덕산네오룩스 주식회사 2016-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180201621-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 ATM 4297/4885KDM4E 1034/4885L3MBTL1 1035/4885
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 ATM 4361/4885KDM4E 1121/4885L3MBTL1 561/4885
US-10717744-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof PIEZO1, OCIAD1, LEF1 ATM 4361/4885KDM4E 1121/4885L3MBTL1 561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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