Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15702069 | 0.94 | SSTR3 (0.51) | SSTR3HDAC8CTSLSIRT2SIRT1 | |
| SCHEMBL16847583 | 0.93 | HDAC8 (0.55) | HDAC8SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL15702064 | 0.93 | SSTR3 (0.52) | SSTR3HDAC8CTSLSIRT2SIRT1 | |
| SCHEMBL25361958 | 0.91 | SSTR3 (0.50) | SSTR3HDAC8CTSLSIRT2SIRT1 | |
| SCHEMBL25361946 | 0.91 | SSTR3 (0.50) | SSTR3HDAC8CTSLSIRT2SIRT1 | |
| SCHEMBL22698598 | 0.90 | HDAC8 (0.51) | HDAC8SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL29649478 | 0.88 | SSTR3 (0.44) | SSTR3HDAC8CTSLSIRT2SIRT1 | |
| SCHEMBL10198897 | 0.87 | SSTR3 (0.44) | SSTR3HDAC8CTSLSIRT2SIRT1 | |
| SCHEMBL15702071 | 0.87 | SSTR3 (0.45) | SSTR3HDAC8CTSLSIRT2SIRT1 | |
| SCHEMBL16847584 | 0.87 | HDAC8 (0.57) | HDAC8SIRT2SIRT1SIRT3SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160279261-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160279261-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | DNPEP, LNPEP, BCR | SSTR3 217/4885HDAC8 2826/4885CTSL 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.