Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18102711 | 0.99 | ITGB1 (0.39) | ITGB1ITGA4SIRT1SIRT2SIRT3 | |
| SCHEMBL16847441 | 0.98 | ITGB1 (0.38) | ITGB1ITGA4SIRT1SIRT2SIRT3 | |
| SCHEMBL16847405 | 0.90 | ITGB1 (0.37) | ITGB1ITGA4SIRT1SIRT2SIRT3 | |
| SCHEMBL16847795 | 0.89 | ITGB1 (0.41) | ITGB1ITGA4SIRT1SIRT2SIRT3 | |
| SCHEMBL18102709 | 0.89 | ITGB1 (0.41) | ITGB1ITGA4SIRT1SIRT2SIRT3 | |
| SCHEMBL16847794 | 0.88 | SIRT2 (0.40) | ITGB1ITGA4SIRT1SIRT2SIRT3 | |
| SCHEMBL17801788 | 0.87 | ITGB1 (0.40) | ITGB1ITGA4SIRT1SIRT2SIRT3 | |
| SCHEMBL16847407 | 0.87 | ITGB1 (0.40) | ITGB1ITGA4SIRT1SIRT2SIRT3 | |
| SCHEMBL16847425 | 0.87 | SIRT2 (0.40) | ITGB1ITGA4SIRT1SIRT2SIRT3 | |
| SCHEMBL22698346 | 0.87 | SPHK1 (0.35) | ITGB1ITGA4SIRT1SIRT2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082875-B1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH INC (US) | 2020-11-25 | — | — | EP | disclosed |
| US-10632210-B2 | Peptidomimetic compounds and antibody-drug conjugates thereof | GENENTECH, INC. (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190083643-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2019-03-21 | — | — | US | disclosed |
| US-20160279261-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10632210-B2 | Peptidomimetic compounds and antibody-drug conjugates thereof | DNPEP, LNPEP, BCR | ITGB1 1803/4885ITGA4 2596/4885SIRT1 3409/4885 |
| US-20190083643-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | DNPEP, LNPEP, BCR | ITGB1 1803/4885ITGA4 2596/4885SIRT1 3409/4885 |
| US-20160279261-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | DNPEP, LNPEP, BCR | ITGB1 1803/4885ITGA4 2596/4885SIRT1 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.