Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16847441 | 0.89 | ITGB1 (0.38) | SPHK1SPHK2SIRT1SIRT2ITGB1 | |
| SCHEMBL18102738 | 0.87 | ITGB1 (0.40) | SPHK1SPHK2SIRT1SIRT2ITGB1 | |
| SCHEMBL18102711 | 0.86 | ITGB1 (0.39) | SPHK1SPHK2SIRT1SIRT2ITGB1 | |
| SCHEMBL21949981 | 0.85 | SIRT2 (0.36) | SPHK1SPHK2SIRT1SIRT2KLKB1 | |
| SCHEMBL21846594 | 0.84 | OPRM1 (0.32) | SIRT1SIRT2 | |
| SCHEMBL16847405 | 0.81 | ITGB1 (0.37) | SPHK1SIRT1SIRT2ITGB1ITGA4 | |
| SCHEMBL16847741 | 0.81 | CA1 (0.46) | SIRT1SIRT2 | |
| SCHEMBL16847625 | 0.80 | SIRT2 (0.37) | SIRT1SIRT2ITGB1ITGA4KLKB1 | |
| SCHEMBL17801788 | 0.78 | ITGB1 (0.40) | SIRT1SIRT2ITGB1ITGA4PLG | |
| SCHEMBL18722953 | 0.78 | BDKRB2 (0.39) | KLKB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082875-B1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH INC (US) | 2020-11-25 | — | — | EP | disclosed |