Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | CA9 | Q16790 | 6/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417067 | 0.87 | PTGS2 (0.56) | PTGS2PTGS1KDM4EHPGDMEN1 | |
| SCHEMBL12416949 | 0.80 | CA2 (0.62) | PTGS2PTGS1ALDH1A1CA2CA9 | |
| SCHEMBL12416826 | 0.78 | CA2 (0.72) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL2314949 | 0.76 | KDM4E (0.73) | KDM4EHPGDMEN1ALDH1A1GAA | |
| SCHEMBL24175860 | 0.74 | KDM4E (0.58) | KDM4EHPGDMEN1ALDH1A1LMNA | |
| SCHEMBL24175847 | 0.74 | KDM4E (0.58) | KDM4EHPGDMEN1ALDH1A1LMNA | |
| SCHEMBL24175864 | 0.73 | KDM4E (0.57) | KDM4EHPGDMEN1ALDH1A1LMNA | |
| SCHEMBL24175867 | 0.73 | KDM4E (0.60) | KDM4EHPGDMEN1ALDH1A1LMNA | |
| SCHEMBL26973856 | 0.73 | KDM4E (0.57) | KDM4EHPGDMEN1ALDH1A1LMNA | |
| SCHEMBL12787878 | 0.72 | KDM4E (1.00) | KDM4EHPGDMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11568956-B2 | Methods for identifying inhibitors of amyloid protein aggregation | TREVENTIS CORPORATION (US) | 2023-01-31 | — | — | US | disclosed |
| US-20190050526-A1 | METHODS FOR IDENTIFYING INHIBITORS OF AMYLOID PROTEIN AGGREGATION | TREVENTIS CORPORATION (US) | 2019-02-14 | — | — | US | disclosed |
| US-20160283652-A1 | METHODS FOR IDENTIFYING INHIBITORS OF AMYLOID PROTEIN AGGREGATION | TREVENTIS CORPORATION (US) | 2016-09-29 | — | — | US | disclosed |
| US-20160283652-A1 | METHODS FOR IDENTIFYING INHIBITORS OF AMYLOID PROTEIN AGGREGATION | TREVENTIS CORPORATION (US) | 2016-09-29 | — | — | US | disclosed |