Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | BAX | Q07812 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18108045 | 0.84 | LTA4H (0.41) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL18108197 | 0.80 | CA4 (0.40) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL18108394 | 0.80 | LTA4H (0.38) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL18108028 | 0.78 | LTA4H (0.36) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL1042948 | 0.78 | LTA4H (0.45) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL1041459 | 0.78 | LTA4H (0.45) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL1039302 | 0.78 | LTA4H (0.45) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL1042227 | 0.78 | LTA4H (0.45) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL1040748 | 0.78 | LTA4H (0.45) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL1042629 | 0.78 | LTA4H (0.45) | LTA4HTSHRCA4KCNA3CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884928-B2 | Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group | BRIDGESTONE CORPORATION (JP) | 2018-02-06 | — | — | US | disclosed |
| US-20160289354-A1 | POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP | BRIDGESTONE CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |