SCHEMBL1042948

SCHEMBL1042948

Cl[Si](Cl)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.45
TSHR P16473 2/20 0.45
CA4 P22748 1/20 0.41
KCNA3 P22001 1/20 0.38
CA5A P35218 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
NR1H2 P55055 1/20 0.35
BAX Q07812 1/20 0.35
MAOA P21397 1/20 0.35
KDM4E B2RXH2 2/20 0.34
KMT2A Q03164 2/20 0.34
KCNH2 Q12809 1/20 0.34
GLA P06280 1/20 0.34
MAPT P10636 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RECQL P46063 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5032254 0.85 CA4 (0.46) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1040748 0.82 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1042227 0.82 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL5032266 0.79 LTA4H (0.41) LTA4HTSHRCA4KCNA3KDM4E
SCHEMBL5028328 0.79 CA4 (0.36) LTA4HTSHRCA4CA5ACA5B
SCHEMBL18108136 0.78 LTA4H (0.41) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1130623 0.78 CA4 (0.43) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1130100 0.78 CA4 (0.43) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL18108279 0.78 LTA4H (0.41) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1130703 0.78 CA4 (0.43) LTA4HTSHRCA4KCNA3CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700693-B2 Conjugated diene rubber compostion, process for producing the same and rubber vulcanizate ZEON CORPORATION (JP) 2010-04-20 US claimed
US-7528199-B2 Conjugated-diolefin (co)polymer rubber and process for producing the same JSR CORPORATION (JP) 2009-05-05 US claimed
EP-0890580-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORP (JP) 2003-09-17 EP claimed
US-6228908-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORPORATION (JP) 2001-05-08 US claimed
US-6008295-A FIRST COUPLING THE LIVING DIENE POLYMER OR COPOLYMER CHAINS OBTAINED BY ANIONIC POLYMERIZATION WITH A TIN HALIDE COUPLING AGENT AND THEN TERMINATING THE REMAINING LIVING POLYMER OR COPOLYMER CHAINS WITH A HYDROCARBOXYSILANE; TIRE TREADS BRIDGESTONE CORPORATION (JP) 1999-12-28 US claimed
EP-0890580-A1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds Bridgestone Corporation (JP) 1999-01-13 EP claimed
US-5118769-A Using coordination catalyst TOYO SODA MANUFACTURING CO., LTD. (JP) 1992-06-02 US claimed
US-4804726-A USING COORDINATION CATALYSTS COMPRISING COMPOUNDS OF MAGNESIUM, TITANIUM, ALUMINUM AND SILICON Ioyo Soda Manufacturing Co., Ltd. (JP) 1989-02-14 US claimed
JP-62227908-A None JP disclosed
JP-3072538-A None JP disclosed
EP-3916045-B1 HIGH STRENGTH HYDROGENATED POLYMERS, AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORP (JP) 2026-05-06 EP disclosed
EP-4662253-A2 METHOD FOR PREPARING MONOMODAL POLYISOPRENE WITH DILITHIUM INITIATORS BRIDGESTONE CORPORATION (JP) 2025-12-17 EP disclosed
EP-4646450-A1 LINEAR TELECHELIC DIENE COPOLYMERS AND THEIR USE IN TIRE COMPONENTS BRIDGESTONE CORPORATION (JP) 2025-11-12 EP disclosed
US-20250236693-A1 RESIN COMPOSITION, AND MOLDED PRODUCT, CURED PRODUCT, FILM, COMPOSITE MATERIAL, CURED COMPOSITE MATERIAL, LAMINATE, METAL FOIL WITH RESIN, AND VARNISH FOR CIRCUIT BOARD MATERIAL OBTAINEDTHEREFROM NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2025-07-24 US disclosed
US-4804726-A USING COORDINATION CATALYSTS COMPRISING COMPOUNDS OF MAGNESIUM, TITANIUM, ALUMINUM AND SILICON Ioyo Soda Manufacturing Co., Ltd. (JP) 1989-02-14 US disclosed
EP-0275317-A1 PROCESS FOR PRODUCING STEREOREGULAR POLYOLEFINS TOSOH CORPORATION (JP) 1988-07-27 EP disclosed
JP-S62227908-A PRODUCTION OF SILANE COMPOUND-MODIFIED POLYMER JAPAN SYNTHETIC RUBBER CO LTD 1987-10-06 JP disclosed
EP-0230707-A2 Manufacturing method of polyolefin TOYO SODA MANUFACTURING CO., LTD. (JP) 1987-08-05 EP disclosed
US-4551439-A Solid catalyst component for olefin polymerization and process for producing same CHISSO CORPORATION (JP) 1985-11-05 US disclosed
US-4507448-A Process for the production of polyolefins NIPPON OIL CO., LTD. (JP) 1985-03-26 US disclosed