Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249171 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL31286348 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL133207 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL9453441 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL8160689 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL10894089 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL17966475 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL131777 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL21817839 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL25338689 | 0.97 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884928-B2 | Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group | BRIDGESTONE CORPORATION (JP) | 2018-02-06 | — | — | US | disclosed |
| US-20160289354-A1 | POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP | BRIDGESTONE CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |