SCHEMBL133207

SCHEMBL133207

CCCCCC[Si](Cl)(CCCCCC)CCCCCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 3/20 0.45
DNM1 Q05193 7/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6249171 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL31286348 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL9453441 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8160689 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL18108232 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL10894089 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL17966475 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL131777 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL21817839 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL25338689 0.97 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 816 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4028379-B1 IMPROVED METHOD FOR THE PREPARATION OF CYCLOPROYL COMPOUNDS FROM ALKENES SALTIGO GMBH (DE) 2025-11-19 EP claimed
CN-119059879-A Cyclopropanation of substituted olefins 国际香料和香精公司 2024-12-03 CN claimed
WO-2024232632-A1 TRANSITION METAL SUPPORTED CATALYST WITH IMPROVED HYDROGENATION ACTIVITY AND USE THEREOF 한양대학교 산학협력단 2024-11-14 WO claimed
US-20240352315-A1 METHODS AND COMPOSITIONS FOR ENHANCED DISPERSION OF PHOSPHOR IN A POLYMERIC MATRIX BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-10-24 US claimed
CN-117982404-A Ocular surface slow release drug delivery implant capable of adjusting drug release rate and preparation method thereof 复旦大学附属眼耳鼻喉科医院 2024-05-07 CN claimed
US-20240010511-A1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF PHOSPHOR AND ITS INCORPORATION IN A POLYMER MATRIX FOR LIGHT CONVERSION SOLGRO, INC. (US) 2024-01-11 US claimed
US-20220348526-A1 Improved process for preparing cyclopropyl compounds from alkenes SALTIGO GMBH (DE) 2022-11-03 US claimed
EP-4028379-A1 IMPROVED PROCESS FOR PREPARING CYCLOPROPYL COMPOUNDS FROM ALKENES Saltigo GmbH (DE) 2022-07-20 EP claimed
CN-114401938-A Improved process for the preparation of cyclopropyl compounds from olefins 赛拓有限责任公司 2022-04-26 CN claimed
CN-113502102-A Heat-insulating coating and preparation method thereof 贵州广毅节能环保科技有限公司 2021-10-15 CN claimed
JP-4796259-B2 2011-10-19 JP claimed
US-20110124001-A1 Compositions For Use In Detection Of Multiple Analytes SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) 2011-05-26 US claimed
EP-1979019-A2 BIOACTIVE MATERIAL DELIVERY SYSTEMS COMPRISING SOL-GEL COMPOSITIONS Medlogics Device Corporation (US) 2008-10-15 EP claimed
WO-2007092043-A2 BIOACTIVE MATERIAL DELIVERY SYSTEMS COMPRISING SOL-GEL COMPOSITIONS MEDLOGICS DEVICE CORPORATION (US) 2007-08-16 WO claimed
US-20070071789-A1 Bioactive Material Delivery Systems Comprising Sol-Gel Compositions MEDLOGICS DEVICE CORPORATION (US) 2007-03-29 US claimed
EP-1305632-A2 COMPOSITIONS FOR DETECTION OF MULTIPLE ANALYTES Dade Behring Marburg GmbH (DE) 2003-05-02 EP claimed
EP-0759439-B1 Synthesis of silylated cyanohydrins CREANOVA INC (US) 2002-09-18 EP claimed
WO-2001084157-A2 COMPOSITIONS FOR DETECTION OF MULTIPLE ANALYTES DADE BEHRING MARBURG GMBH (DE) 2001-11-08 WO claimed
EP-0759439-A2 Synthesis of silylated cyanohydrins HÜLS AMERICA INC. (US) 1997-02-26 EP claimed
US-5594156-A REACTING AN ALDEHYDE OR KETONE WITH HYDROGEN CYANIDE, A TRISUBSTITUTED HALOSILANE AND A CORRESPONDINGLY SUBSTITUTED DISILAZANE OR SILYL AMINE HULS AMERICA INC. (US) 1997-01-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124001-A1 Compositions For Use In Detection Of Multiple Analytes CYBB, CD14, MPO TSHR 3628/4885THRB 3907/4885ALDH1A1 950/4885
US-20220348526-A1 Improved process for preparing cyclopropyl compounds from alkenes CYP4F3, CXXC4, ZRANB2 TSHR 3420/4885THRB 4657/4885ALDH1A1 642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.