SCHEMBL131777

SCHEMBL131777

CCCCCCCC[Si](Cl)(CCCCCCCC)CCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 3/20 0.45
DNM1 Q05193 7/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6249171 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL31286348 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL133207 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL9453441 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8160689 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL18108232 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL10894089 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL17966475 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL21817839 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL25338689 0.97 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037429-A Novel surface function auxiliary agent and preparation method and application thereof 青岛华邦高能材料有限公司 2026-05-15 CN claimed
WO-2024232632-A1 TRANSITION METAL SUPPORTED CATALYST WITH IMPROVED HYDROGENATION ACTIVITY AND USE THEREOF 한양대학교 산학협력단 2024-11-14 WO claimed
US-9676874-B2 Processes for preparing aminosilane functionalized polymers BRIDGESTONE CORPORATION (JP) 2017-06-13 US claimed
US-20160152756-A1 PROCESSES FOR PREPARING AMINOSILANE FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2016-06-02 US claimed
CN-122037429-A Novel surface function auxiliary agent and preparation method and application thereof 青岛华邦高能材料有限公司 2026-05-15 CN disclosed
US-20260071068-A1 RESIN-EXTENDED RUBBER AND PROCESS FOR PREPARING BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2026-03-12 US disclosed
EP-4055098-B1 TIRE HAVING TREAD OF SPECIFIED RUBBER COMPOSITION AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2025-12-24 EP disclosed
US-12466214-B2 Tire tread rubber composition BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-11-11 US disclosed
US-20250333585-A1 Tire Tread Rubber Composition BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-10-30 US disclosed
US-12410274-B2 Anionic dispersion polymerization process to make random copolymer rubber BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-12371552-B2 Tire tread rubber composition and related methods BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-07-29 US disclosed
US-12370830-B2 Tire tread rubber composition BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-07-29 US disclosed
US-4985328-A Metal Complex Charge Control Agents HITACHI CHEMICAL CO., LTD. (JP) 1991-01-15 US disclosed
EP-0360617-A2 Dry toner, dry developer and process for forming images Hitachi Chemical Co., Ltd. (JP) 1990-03-28 EP disclosed
US-4686166-A HIGH IMAGE DENSITY, ANTIFOGGING AGENT HITACHI CHEMICAL CO. (JP) 1987-08-11 US disclosed
US-4595777-A Reacting alkylchlorosilane with trialkylaluminum compound GULF RESEARCH & DEVELOPMENT COMPANY (US) 1986-06-17 US disclosed
US-4585723-A SILICON DIOXIDE PARTICLES MADE HYDROPHOBIC KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-29 US disclosed
EP-0011456-B1 ORGANOTIN COMPOUNDS AND RESINS OR POLYMERS STABILIZED THEREWITH M & T CHEMICALS, INC. (US) 1983-09-07 EP disclosed
US-4254017-A HEAT STABILIZER FOR POLYVINYL CHLORIDE M&T CHEMICALS INC. (US) 1981-03-03 US disclosed
US-4229558-A HAVING HIGH ISOTACTIC INDEX BY USING A CATALYST PREPARED FROM A MAGNESIUM GRIGNARD REAGENT, TITANIUM HALIDE AN ETHER AND A CARBOXYLIC ESTER COMBINED WITH AN ORGANOALUMINUM COMPOUND MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1980-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071068-A1 RESIN-EXTENDED RUBBER AND PROCESS FOR PREPARING RER1, SMCHD1, REL TSHR 3188/4885THRB 1366/4885ALDH1A1 2597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.