SCHEMBL1811045

SCHEMBL1811045

C=CCC(O)COc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
CYP2D6 P10635 4/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ADRB2 P07550 1/20 0.51
ADRB1 P08588 1/20 0.51
ADRB3 P13945 1/20 0.51
KDM4E B2RXH2 1/20 0.50
MAPT P10636 2/20 0.49
TSHR P16473 1/20 0.49
HIF1A Q16665 1/20 0.49
RECQL P46063 1/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
OPRM1 P35372 1/20 0.46
OPRD1 P41143 1/20 0.46
AGER Q15109 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL11626916 0.92 LMNA (0.46) LMNACYP2D6L3MBTL1ADRB2ADRB1
SCHEMBL9419530 0.85 THRB (0.46) LMNAL3MBTL1KDM4ERECQLSMN1; SMN2
SCHEMBL8644617 0.82 LMNA (0.50) LMNACYP2D6L3MBTL1ADRB2ADRB1
SCHEMBL11513661 0.82 USP2 (0.55) LMNACYP2D6KDM4EMAPTTSHR
SCHEMBL11513728 0.82 KMT2A (0.52) LMNACYP2D6L3MBTL1ADRB3KDM4E
SCHEMBL8644621 0.82 LMNA (0.50) LMNACYP2D6L3MBTL1ADRB2ADRB1
SCHEMBL11514601 0.82 TSHR (0.47) LMNACYP2D6MAPTTSHRMEN1
SCHEMBL2108370 0.82 THRB (0.46) LMNACYP2D6L3MBTL1ADRB2ADRB1
SCHEMBL267463 0.82 LMNA (0.68) LMNACYP2D6L3MBTL1ADRB2ADRB1
SCHEMBL11950503 0.81 CYP2D6 (0.49) LMNACYP2D6L3MBTL1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158088-B2 Extractant compositions for co-extracting cesium and strontium, a method of separating cesium and strontium from an aqueous feed, and calixarene compounds BATTELLE ENERGY ALLIANCE, LLC (US) 2012-04-17 US claimed
US-20100116749-A1 EXTRACTANT COMPOSITIONS FOR CO EXTRACTING CESIUM AND STRONTIUM, A METHOD OF SEPARATING CESIUM AND STRONTIUM FROM AN AQUEOUS FEED, CALIXARENE COMPOUNDS, AND AN ALCOHOL MODIFIER UT-BATTELLE, LLC 2010-05-13 US claimed
CN-101028266-B Lung medicine-feeding preparation containing Mulinong LUNAN PHARM GROUP CORP 2010-05-12 CN claimed
CN-101028266-A Lung medicine-feeding preparation containing Mulinong LUNAN PHARMACEUTICAL GROUP CO (CN) 2007-09-05 CN claimed
EP-0774957-B1 AQUEOUS FOAMABLE COMPOSITION TILLOTTS PHARMA AG (CH) 2001-10-31 EP claimed
US-5679574-A SOLVENT EXTRACTION IN THE PRESENCE OF A DRYING AGENT, FILTRATION, FORMATION OF AN AQUEOUS EMULSION AND COMPARISON OF TURBIDIMETRIC RESPONSE TO A STANDARD CURVE; EFFICIENCY ENSYS ENVIRONMENTAL PRODUCTS, INC. (US) 1997-10-21 US claimed
CN-1158565-A aqueous foam composition TILLOTTS PHARMA AG (CH) 1997-09-03 CN claimed
EP-0492615-B1 Process for producing biguanide derivative IDEMITSU KOSAN CO (JP) 1995-03-08 EP claimed
US-5286905-A Heating hydrogen halide salt of phenoxyalkylamine with dicyandiamide in paraffinic hydrocarbon solvent IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-02-15 US claimed
EP-0136727-B2 AROMATIC POLYAMIDE YARN IMPREGNATED WITH LUBRICATING PARTICLES, A PROCESS FOR THE MANUFACTURE OF SUCH A YARN, AND PACKING MATERIAL OR ROPE CONTAINING THIS YARN AKZO N.V. (NL) 1992-10-07 EP claimed
US-5133875-A System and method for treating wastewater containing industrial esters UNIVERSITY OF SOUTH FLORIDA IN BEHALF OF BOARD OF REGENTS OF THE STATE OF FLORIDA (US) 1992-07-28 US claimed
EP-0492615-A1 Process for producing biguanide derivative IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-01 EP claimed
EP-0136727-B1 AROMATIC POLYAMIDE YARN IMPREGNATED WITH LUBRICATING PARTICLES, A PROCESS FOR THE MANUFACTURE OF SUCH A YARN, AND PACKING MATERIAL OR ROPE CONTAINING THIS YARN AKZO N.V. (NL) 1987-08-12 EP claimed
EP-0136727-A1 Aromatic polyamide yarn impregnated with lubricating particles, a process for the manufacture of such a yarn, and packing material or rope containing this yarn AKZO N.V. (NL) 1985-04-10 EP claimed
US-4328279-A OF THERMOPLASTIC FIBERS, SODIUM DIOCTYL SULFOSUCCINATE AND NONIONI KIMBERLY-CLARK CORPORATION (US) 1982-05-04 US claimed
EP-3262009-A1 USE OF CSH-SEED MODIFIED FIBERS IN OIL FIELD APPLICATIONS BASF SE (DE) 2018-01-03 EP disclosed
WO-2016135182-A1 USE OF CSH-SEED MODIFIED FIBERS IN OIL FIELD APPLICATIONS BASF SE (DE) 2016-09-01 WO disclosed
US-4066675-A PSORIASIS, THROMBOSIS MERCK & CO., INC. (US) 1978-01-03 US disclosed
US-4031055-A ISOTHIAZOLONE; MILDEW RESISTANCE ROHM AND HAAS COMPANY (US) 1977-06-21 US disclosed
US-4018802-A SKIN DISEASES, GROWTH HORMONE STIMULANTS, THROMBUS PREVENTION, IMMUNOLOGY MERCK & CO., INC. (US) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100116749-A1 EXTRACTANT COMPOSITIONS FOR CO EXTRACTING CESIUM AND STRONTIUM, A METHOD OF SEPARATING CESIUM AND STRONTIUM FROM AN AQUEOUS FEED, CALIXARENE COMPOUNDS, AND AN ALCOHOL MODIFIER CANX, CBX6, CALD1 LMNA 3538/4885CYP2D6 210/4885L3MBTL1 2892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.