Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851254 | 0.70 | ALDH1A1 (0.32) | LMNAALDH1A1 | |
| SCHEMBL18113204 | 0.68 | KDM4E (0.35) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL24470878 | 0.67 | TSHR (0.46) | MEN1KMT2ALMNAMMP1MMP2 | |
| SCHEMBL12044988 | 0.67 | MEN1 (0.39) | MEN1KMT2ALMNAMMP1MMP2 | |
| SCHEMBL320703 | 0.66 | ALDH1A1 (0.46) | MEN1KMT2ALMNAMMP1MMP2 | |
| SCHEMBL10916004 | 0.66 | ELANE (0.33) | LMNAALDH1A1 | |
| SCHEMBL18113109 | 0.66 | LMNA (0.32) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL18113224 | 0.66 | CYP3A4 (0.33) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL23690521 | 0.66 | TSHR (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27844041 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277736-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016156473-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-10-06 | — | — | WO | disclosed |