Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814978 | 0.87 | MCHR1 (0.43) | HRH3MCHR1KCNH2 | |
| SCHEMBL1809300 | 0.79 | HRH3 (0.62) | HRH3KCNH2 | |
| SCHEMBL1813464 | 0.78 | HRH3 (0.63) | HRH3KCNH2 | |
| Fumaric Acid SCHEMBL1811369 | 0.76 | HRH3 (0.52) | HRH3 | |
| SCHEMBL1814415 | 0.71 | HRH3 (0.52) | HRH3 | |
| SCHEMBL4278988 | 0.70 | DRD2 (0.55) | — | |
| SCHEMBL2322360 | 0.70 | DRD2 (0.55) | — | |
| SCHEMBL6584141 | 0.70 | DRD2 (0.55) | — | |
| SCHEMBL1816405 | 0.70 | HRH3 (0.53) | HRH3 | |
| SCHEMBL1810499 | 0.69 | HRH3 (0.47) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935719-B2 | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH LLC (US) | 2011-05-03 | — | — | US | disclosed |