Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811370 | 0.87 | HRH3 (0.46) | MCHR1KCNH2HRH3 | |
| Fumaric Acid SCHEMBL1814977 | 0.74 | MKNK1 (0.43) | — | |
| SCHEMBL4942172 | 0.69 | MKNK1 (0.50) | — | |
| Acetic Acid SCHEMBL2500600 | 0.69 | ACHE (0.53) | — | |
| Acetic Acid SCHEMBL2904677 | 0.69 | ACHE (0.53) | — | |
| SCHEMBL42501 | 0.68 | ACHE (0.58) | CYP2D6 | |
| SCHEMBL330609 | 0.68 | ACHE (0.58) | CYP2D6 | |
| SCHEMBL14793661 | 0.68 | ACHE (0.58) | CYP2D6 | |
| SCHEMBL239922 | 0.68 | ACHE (0.58) | CYP2D6 | |
| Bromide SCHEMBL2899465 | 0.67 | ACHE (0.56) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935719-B2 | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH LLC (US) | 2011-05-03 | — | — | US | disclosed |