Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | PIKFYVE | Q9Y2I7 | 3/20 | 0.57 |
| ▸ | FES | P07332 | 1/20 | 0.57 |
| ▸ | FER | P16591 | 1/20 | 0.57 |
| ▸ | TYK2 | P29597 | 1/20 | 0.57 |
| ▸ | FRK | P42685 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.57 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18115258 | 1.00 | LMNA (0.70) | LMNAMAPTKDM4EHPGDSENP7 | |
| SCHEMBL428572 | 0.91 | KDM4E (0.75) | LMNAMAPTKDM4EHPGDSENP7 | |
| SCHEMBL428571 | 0.91 | KDM4E (0.75) | LMNAMAPTKDM4EHPGDSENP7 | |
| SCHEMBL18115336 | 0.86 | KDM4E (0.66) | LMNAMAPTKDM4EHPGDSENP7 | |
| SCHEMBL18121498 | 0.86 | KDM4E (0.66) | LMNAMAPTKDM4EHPGDSENP7 | |
| SCHEMBL18618039 | 0.83 | KDM4E (0.64) | LMNAMAPTKDM4EHPGDSENP7 | |
| SCHEMBL18330253 | 0.83 | MAPT (1.00) | LMNAMAPTKDM4EHPGDSENP7 | |
| SCHEMBL4143852 | 0.81 | PIK3CA (0.57) | MAPTPIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL429035 | 0.81 | MAPT (0.77) | LMNAMAPTKDM4EHPGDSENP7 | |
| SCHEMBL429036 | 0.81 | MAPT (0.77) | LMNAMAPTKDM4EHPGDSENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180271873-A1 | METHODS FOR TREATING VIRAL INFECTIONS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH | 2018-09-27 | — | — | US | disclosed |
| WO-2016161176-A1 | METHODS FOR TREATING VIRAL INFECTIONS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180271873-A1 | METHODS FOR TREATING VIRAL INFECTIONS | HAVCR2, CCL11, EIF2AK2 | LMNA 2400/4885MAPT 3102/4885KDM4E 4324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.