Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metolachor SCHEMBL18115411 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB | |
| Metolachor SCHEMBL21385 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB | |
| S-Metolachlor SCHEMBL31170483 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB | |
| Metolachor SCHEMBL29357706 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB | |
| Metolachor SCHEMBL18115413 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB | |
| S-Metolachlor SCHEMBL118065 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB | |
| Metolachor SCHEMBL8190790 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB | |
| Metolachor SCHEMBL29397526 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB | |
| Metolachor SCHEMBL338302 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB | |
| Metolachor SCHEMBL20723457 | 0.89 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ASMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280260-A1 | HERBICIDAL MIXTURES | Syngenta Participations AG (CH) | 2018-02-14 | — | — | EP | disclosed |
| EP-3277089-A1 | HERBICIDAL MIXTURES | Syngenta Participations AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016162265-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-13 | — | — | WO | disclosed |
| WO-2016156241-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |