Sugi Predict

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Metolachor

Metolachor

SCHEMBL338302

CCc1cccc(C)c1N(C(=O)CCl)[C@H](C)COC

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.59
▸ MEN1 O00255 4/20 0.59
▸ KMT2A Q03164 4/20 0.59
▸ SMN1; SMN2 Q16637 2/20 0.59
▸ THRB P10828 2/20 0.59
▸ MAPT P10636 1/20 0.57
▸ TP53 P04637 5/20 0.55
▸ TDP1 Q9NUW8 3/20 0.55
▸ CYP3A4 P08684 1/20 0.55
▸ NR1I2 O75469 1/20 0.46
▸ LMNA P02545 1/20 0.40
▸ KDM4E B2RXH2 2/20 0.39
▸ PLA2G1B P04054 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ ATG4B Q9Y4P1 1/20 0.38
▸ RORC P51449 1/20 0.37
▸ HPGD P15428 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metolachor SCHEMBL29357706 1.00 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ASMN1; SMN2THRB
Metolachor SCHEMBL29397526 1.00 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ASMN1; SMN2THRB
S-Metolachlor SCHEMBL31170483 1.00 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ASMN1; SMN2THRB
Metolachor SCHEMBL18115413 1.00 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ASMN1; SMN2THRB
Metolachor SCHEMBL8190790 1.00 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ASMN1; SMN2THRB
S-Metolachlor SCHEMBL118065 1.00 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ASMN1; SMN2THRB
Metolachor SCHEMBL21385 1.00 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ASMN1; SMN2THRB
Metolachor SCHEMBL20723468 0.99 ALDH1A1 (0.58) ALDH1A1MEN1KMT2ASMN1; SMN2THRB
Metolachor SCHEMBL20723457 0.99 ALDH1A1 (0.58) ALDH1A1MEN1KMT2ASMN1; SMN2THRB
Metolachor SCHEMBL8060026 0.95 ALDH1A1 (0.56) ALDH1A1MEN1KMT2ASMN1; SMN2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10925279-B2 Pickering emulsion formulations SYNGENTA PARTICIPATIONS AG (CH) 2021-02-23 — — US claimed
US-8563471-B2 Submicron mesotrione compositions SYNGENTA CROP PROTECTION LLC (US) 2013-10-22 — — US claimed
EP-1691605-B1 SUBMICRON MESOTRIONE COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2012-04-18 — — EP claimed
US-20100292079-A1 PICKERING EMULSION FORMULATIONS SYNGENTA CROP PROTECTION, INC. (US) 2010-11-18 — — US claimed
US-20100234230-A1 PICKERING EMULSION FORMULATIONS SYNGENTA CROP PROTECTION, INC. (US) 2010-09-16 — — US claimed
US-20070225169-A1 Submicron Mesotrione Compositions SYNGENTA CROP PROTECTION AG (CH) 2007-09-27 — — US claimed
EP-1691605-A4 SUBMICRON MESOTRIONE COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2007-02-21 — — EP claimed
EP-1691605-A2 SUBMICRON MESOTRIONE COMPOSITIONS Syngenta Participations AG (CH) 2006-08-23 — — EP claimed
WO-2005055714-A2 SUBMICRON MESOTRIONE COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2005-06-23 — — WO claimed
EP-0088049-B1 HERBICIDAL MIXTURES CIBA-GEIGY AG (CH) 1985-10-23 — — EP claimed
CN-114097784-B Emulsifiable concentrate containing metolachlor and sulfenamide and preparation method thereof 山东润博生物科技有限公司 2024-01-26 — — CN disclosed
CN-116887675-A Herbicidal compositions comprising imidazolinone-based acetolactate synthase inhibitors and uses thereof 安道麦阿甘有限公司 2023-10-13 — — CN disclosed
US-20220125048-A1 HERBICIDAL COMPOSITIONS AND METHODS SEPRO CORPORATION (US) 2022-04-28 — — US disclosed
CN-114097784-A Missible oil containing s-metolachlor and sulfentrazone and preparation method thereof 山东润博生物科技有限公司 2022-03-01 — — CN disclosed
US-11026423-B2 Herbicidal compositions and methods SEPRO CORPORATION (US) 2021-06-08 — — US disclosed
US-20050233907-A1 Herbicidal composition SYNGENTA CROP PROTECTION AG (CH) 2005-10-20 — — US disclosed
WO-2005055714-A2 SUBMICRON MESOTRIONE COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2005-06-23 — — WO disclosed
WO-2005055716-A2 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2005-06-23 — — WO disclosed
US-6890885-B2 Herbicidal composition SYNGENTA CORP PROTECTION, INC. (US) 2005-05-10 — — US disclosed
US-20040106519-A1 Herbicidal composition SYNGENTA CROP PROTECTION, INC. 2004-06-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234230-A1 PICKERING EMULSION FORMULATIONS FLOT1, OSR1, ACHE ALDH1A1 2604/4885MEN1 2375/4885KMT2A 2934/4885
US-20040106519-A1 Herbicidal composition DDT, ACHE, CYP1B1 ALDH1A1 118/4885MEN1 3704/4885KMT2A 919/4885
US-20050233907-A1 Herbicidal composition ADH5, ADH1C, AQP3 ALDH1A1 81/4885MEN1 3156/4885KMT2A 1324/4885
US-20100292079-A1 PICKERING EMULSION FORMULATIONS DDT, ACHE, FLOT1 ALDH1A1 3397/4885MEN1 2008/4885KMT2A 1921/4885
US-10925279-B2 Pickering emulsion formulations FLOT1, OSR1, ACHE ALDH1A1 2604/4885MEN1 2375/4885KMT2A 2934/4885
US-20070225169-A1 Submicron Mesotrione Compositions DDT, NDUFB5, NOTUM ALDH1A1 824/4885MEN1 2304/4885KMT2A 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.