Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18116682 | 0.87 | THRB (0.42) | THRBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10858115 | 0.84 | THRB (0.47) | THRBALDH1A1MAOBCYP11B1CYP11B2 | |
| SCHEMBL18116698 | 0.82 | THRB (0.39) | THRBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7214471 | 0.80 | THRB (0.74) | THRBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL18116303 | 0.79 | THRB (0.41) | THRBCYP1A1CYP1B1PPARD | |
| SCHEMBL6733323 | 0.78 | ESR1 (0.56) | THRBCYP1A1CYP1B1 | |
| SCHEMBL14445729 | 0.75 | THRB (0.61) | THRBSMN1; SMN2ALDH1A1KDM4ECYP1A1 | |
| SCHEMBL11986138 | 0.73 | PRSS1 (0.40) | THRBNPC1CYP1A1CYP1B1MAOB | |
| SCHEMBL11508489 | 0.72 | THRB (0.57) | THRBNPC1RAB9AMAOB | |
| SCHEMBL14523540 | 0.72 | THRB (0.57) | THRBSMN1; SMN2NPC1RAB9ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458269-B2 | Polymerizable composition, antireflection film, polarizing plate and image display device each using the same, and water-repellent or oil-repellent film | FUJIFILM CORPORATION (JP) | 2016-10-04 | — | — | US | disclosed |
| US-9458269-B2 | Polymerizable composition, antireflection film, polarizing plate and image display device each using the same, and water-repellent or oil-repellent film | FUJIFILM CORPORATION (JP) | 2016-10-04 | — | — | US | disclosed |